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强梅

2016年07月29日 15:45  点击:[]

强梅

博士、教授、博导
太原市新建南路56号
山西,中国,030001
T
el:0351-4135262
E-mail:qiang5858@sxmu.edu.cn

主讲课程:《儿童青少年卫生学》、《现代儿少卫生学》、《妇幼保健学》和《英文文献导读》。

主要研究方向
1.儿童青少年近视眼发病机制及防治
2.环境污染物的生殖毒性和发育毒性的表观遗传学机制。                  

科研课题
1. 国家自然科学基金项目,81673185.评估出生缺陷风险的父源性表观遗传学标志物--相关印记基因筛选,主持, 在研。
2. 山西省归国人员科研基金项目,2015-051.汞污染致神经管缺陷的表观遗传学病因的探讨, 主持, 在研。

代表性科研论文
1. Zhang W, Tian F, Zheng J, Li S,Qiang M*, Chronic Administration of Benzo(a)pyrene Induces Memory Impairment and Anxiety-Like Behavior and Increases of NR2B DNA Methylation.PLOS ONE,2016, 11(2): e0149574. doi:10.1371/journal.pone.0149574
2. Mei Qiang*, Ji G. Li1, Ashley D. Denny, Jie-min Yao, Mai Lieu, Kerang Zhang, Stephanie Carreon, Epigenetic mechanisms are involved in the regulation of ethanol consumption in mice. The International Journal of Neuropsychopharmacology, 2015, 18(2):pyu072
3. Guo YQ, Chen YX, Carreon S,
Qiang M*, Chronic Intermittent Ethanol Exposure alters MicroRNA Expressions in Primary Cortical Neuronal Cultures, Alcohol Clin Exp Res., 2012, 36(6): 1058-66. DOI: 10.1111/j.1530-0277.2011.01689.x.
4.
Qiang M*,Denny A,Lieu M,Carreon S,Li J, Histone modifications are involved in chronic intermittent ethanol-induced up-regulation of the NR2B gene transcription,Epigenetics, 2011, 6(9): 1095 - 1104. DOI:10.4161/epi.6.9.16924.
5. Guo JY, Qiang M, Luduena R, The Distribution of (beta)-Tubulin Isotypes in Cultured Neurons from Embryonic, Newborn, and Adult Mouse Brains,
Brain research,2011, 1420:8-18.
6.
Qiang M*,Denny A,Chen J,Ticku MK,Yan B,Henderson G, The site specific CpG demethylation in 5’-regulatory area ofN-Methyl-D-aspartate receptor 2B subunit gene associated with CIE-induced up-regulation of the transcription,PLOS ONE, 2010,5(1): e8798. doi:10.1371/journal.pone.0008798.
7. Qiang M*, Denny A, Ticku MK, Chronic intermittent ethanol treatment selectively alters NMDA receptor subunits surface expression in cultured cortical neurons,
Molecular Pharmacology,2007, 72 (1): 95-102.
8. He W,  Qiang M, Ma W, Valente AJ, Quinones MP, Wang W, Reddick RL, Xiao Q, Ahuja SS, Clark RA, Freeman GL,  Li S, Development of a synthetic promoter for macrophage gene therapy,
Human Gene Therapy, 2006, 17(9):949-59.
9. Qiang M*, Ticku MK, Role of AP-1 in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene up-regulation in mouse cortical neurons,
J Neurochem, 2005, 95(5):1332-1341.
10.Qiang M*, Rani CSS, Ticku MK, Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons,
Mol Pharmacol, 2005, 7(6): 2115-2125.
11.Rani CSS, Qiang M, and Ticku MK, Potential Role of CREB in Ethanol-induced NR2B Gene Transcription in Fetal Mouse Cortical Cells.
Mol Pharmacol. 2005, 67(6):2115–2125.
12.Qiang M, Wang MW, and Andrea J. Elberger, Second trimester prenatal alcohol exposure alters development of rat corpus callosum.
Neurotoxicology and Teratology.2002, 24(6):719-732.
13.Li SL, Valente AJ, Qiang M, Schlegel W, Gamez M, and Clark RA. Multiple PU.1 sites cooperate in the regulation of
p40phoxtranscription during granulocytic differentiation of myeloid cells.Blood,2002, 99(12): 4578-87.
14.Qiang M*, Xie J, Wang H and Qiao JT, Effect of Nitric Oxide Synthesis Inhibition on C-fos Expression in Hippocampus and Cerebral Cortex Following Two Forms of Learning in Rats: An Immunohistochemistry Study.
Behavioral Pharmacology, 1999, 10 (2):215-222.
15.Qiang M, Chen YC, Wang R, Wu FM, Qiao JT. Nitric oxide is involved in the formation of learning and memory in rats: studies using passive avoidance response and Morris water maze task.
Behavioral Pharmacology,1997, 8(2-3):183-7.
16.Qiang M* and Zhao R. Early Signs of Myopia in Chinese Schoolchildren.
Optometry and Vision Science,1994, 71(1): 14-16.

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