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余红梅


余红梅

教授、博导、博士后合作导师、教研室副主任

E-mail: yu@sxmu.edu.cn

教育经历

1998年9月-2001年6月,第四军医大学,卫生统计学,博士

1990年9月-1993年6月,山西医科大学,卫生统计学,硕士

1985年9月-1990年6月,山西医科大学,预防医学,学士

研究工作经历

1993.7至今,山西医科大学公共卫生学院卫生统计学教研室工作

2002年8月-2003年8月,教育部公派美国Medical College of Wisconsin生物统计系访问学者

2020年1月-2020年3月,山西医科大学管理业务骨干海外培养计划University of Auckland统计系访问学者

科研情况

研究方向:队列研究统计分析方法与应用

承担课题

1.基于纵向神经影像数据的痴呆多分类诊断模型与动态筛检策略研究,国家自然科学基金(81973154),2020-2023.

2.基于认知功能多维测量和潜在结构的个体化痴呆风险动态预测模型研究,国家自然科学基金(81673277),2017-2020.

3.2017年度中加(NSFC-CIHR)精神健康与痴呆症合作研究项目联合评审会(81781220359),国家自然科学基金-国际(地区)合作与交流项目,2017.9-2017.12.

4.老年人认知损害和抑郁症共病自然史多状态Markov模型及疾病负担研究,国家自然科学基金(81373106),2014-2017.

5.中美合作阿尔茨海默病生命质量和知识测评量表中文版研制和跨文化调适,山西省国际科技合作项目(2012081047),2012-2013.

6.基于多状态Markov模型和健康相关生存质量的阿尔茨海默病进程定量研究,国家自然科学基金(30972545),2010-2012.

7.阿尔茨海默病自然史多状态Markov模型定量研究,山西省留学回国人员科技活动择优项目,2009-2011.

8.长期生存资料统计建模及医学应用,山西省留学回国人员科研启动基金,2007-2009.

9.可加风险模型用于多状态Markov模型建模的研究,教育部留学回国人员科研启动基金,2007-2009.

10.加速失效时间模型及其在医学研究中的应用,山西省青年科学基金,2004-2006.

11.Cox模型预测评价及预测改善的研究与应用,山西省高校科技研究开发项目,2004-2006.

12.Cox模型诊断及预测评价,全国统计科学研究计划项目,2000-2001.

教学情况

承担教学任务:

课 程 类 别 及 对 象

医学统计学

基础课(五年制临床医学-兆泰班,必修)

医学统计学

基础课(五年制临床医学,必修)

卫生统计学

专业基础课(预防医学本科,必修)

医学统计学

基础课(六年制临床医学留学生,必修)

医学统计学

基础课(硕士研究生,必修课)

高级多元统计方法与SPSS应用

基础课(硕士研究生,选修)

因果关联研究

基础课(硕士研究生,选修)

英文文献导读

专业基础课(博士/硕士研究生,选修)

专业英语

专业基础课(MPH,预防医学本科,选修)

承担课题:

1.多元统计与spss软件应用,2023山西省教育厅研究生教育创新计划项目—研究生优质课程(2023YZ23),2023-2026.

2.依托国家级本科一流课程《医学统计学》虚拟教研室建设,2022年山西省高等学校教学改革创新项目,2022-2024.

3.公共卫生专业学位(MPH)研究生教育模式国际比较研究,全国医学专业学位研究生教育指导委员会研究课题(B2-YX20180306-02),2018-2020.

4.基于国际比较视角的公共卫生专业学位研究生教育模式研究,山西省研究生教育改革研究课题(2018JG42),2018-2020.

5.公共卫生学术型研究生科研能力导向型课程建设-基础理论与方法课程群设置,山西医科大学学术型硕士研究生试点学科课程建设项目,2017-2018.

6.基于OBE导向的医学统计学教学模式创新研究,山西省高等学校教学改革创新项目(2016-38),2016-2018.

参编教材:

1.医学统计学与SPSS软件实现方法(“十四五”普通高等教育本科规划教材),科学出版社,2022,编委

2.流行病学与应用多元统计分析(协和医学院系列规划教材医院领导力及管理系列教材),中国协和医科大学出版社,2022,编委

3.Statistical Methods for Biomedical Research. World Scientific. 2021.

4.Medical Statistics(“十三五国家重点图书出版规划项目”,“一带一路”背景下国际化临床医学丛书),郑州大学出版社,2020,编委

5.中华生物医学统计大辞典单变量统计分册(“十三五”国家重点图书出版规划,2013-2025年国家辞书编篆出版规划,2018年度国家出版基金资助),中国统计出版社,2020,副主编

6.中华生物医学统计大辞典总索引分册(“十三五”国家重点图书出版规划,2013-2025年国家辞书编篆出版规划,2018年度国家出版基金资助),中国统计出版社,2020,主编

学术任职和荣誉

中国统计教育学会第八届理事会常务理事

山西省医学会临床流行病学和循证医学专业委员会副主任委员

中国康复医学会科技管理与评估委员会常务委员

世界华人生活质素学会常务委员

中国卫生信息与健康医疗大数据学会医学统计教育专业委员会常务委员

山西省专家学者协会医学分会常务理事

太原市突发公共卫生事件专家咨询委员会专家暨预测预警组成员

国家自然科学基金评审专家

教育部留学回国人员科研启动基金评审专家

国际生存质量研究会会员

阿尔茨海默学会会员

中国卫生统计杂志审稿人

山西省高校教学名师

山西省三八红旗手

山西医科大学优秀研究生指导教师

山西医科大学优秀共产党员

山西医科大学第十届“育人杯”先进个人

部分发表论文

  1. Fuliang Yi, Hui Yang, Durong Chen, Yao Qin, Hongjuan Han, Jing Cui, Wenlin Bai, Yifei Ma, Rong Zhang, Hongmei Yu*. XGBoost-SHAP-based interpretable diagnostic framework for alzheimer’s disease. BMC Medical Informatics and Decision Making. 2023, 23:137.19.

  2. Jing Cui, Durong Chen, Jiajia Zhang, Yao Qin, Wenlin Bai, Yifei Ma, Rong Zhang, Hongmei Yu*. Landmark model-Based individual dynamic prediction of conversion from mild cognitive impairment to Alzheimer's disease using cognitive screening. Curr Alzheimer Res. 2023 May 26.

  3. Yao Qin, Hongjuan Han, YangLi, Jing Cui, HaixiaJia, Xiaoyan Ge, YifeiMa, WenlinBai, RongZhang, DurongChen, FuliangYi, Hongmei Yu*. Estimatingbidirectionaltransitions andidentifyingpredictors of mild cognitive impairment. Neurology,2023,100(3):e297-e307.

  4. Sidan Du, YingHuang, YifeiMa, Yao Qin, Jing Cui, WenlinBai, Hongjuan Han, RongZhang, Hongmei Yu*.The mediating effects of depression, anxiety, and rapid eye movement sleep behavior disorder on the association between dopaminergic replacement therapy and impulse control disorders in Parkinson's disease.Neurological sciences. 2023. Feb;44(2):557-564.

  5. Yifei Ma, Shujun Xu, Yuxin Luo, Jiantao Li, Lijian Lei, Lu He, Tong Wang, Hongmei Yu,* and Jun Xie*. Model-based analysis of the incidence trends and transmission dynamics of COVID-19 associated with the Omicron variant in representative cities in China, BMC Public Health. 2023.12.

  6. Yifei Ma, Shujun Xu, Ali Dong, Jianhua An, Yao Qin, Hui Yang, Hongmei Yu*. Epidemiological characteristics, spatial clusters and monthly incidence prediction of hand, foot and mouth disease from 2017 to 2022 in Shanxi Province, China. Epidemiol Infect. 2023 Mar 14;151:e54.

  7. Yifei Ma, Shujun Xu, Yuxin Luo, Yao Qin, Jiantao Li, Lijian Lei, Lu He, Tong Wang*, Hongmei Yu,* Jun Xie*. Epidemiological characteristics and transmission dynamics of the COVID-19 outbreak in Hohhot, China: a time-varying SQEIAHR model analysis. Front Public Health. 2023.06. 21

  8. Yifei Ma, Shujun Xu, Yuxin Luo, Junlin Peng, Jiaming Guo, Ali Dong, Zhibin Xu, Jiantao Li, Lijian Lei, Lu He, Tong Wang, Hongmei Yu,* Jun Xie*.Predicting the transmission dynamics of novel coronavirus infection in Shanxi province after the implementation of the 'Class B infectious disease Class B management' policy, Front. Public Health. 2023

  9. Xiaoyan Ge, Kai Cui, Yao Qin, Durong Chen, Hongjuan Han, Hongmei Yu*. Screening strategies and dynamic risk prediction models for Alzheimer’s disease. Journal of Psychiatric Research. 2023,166: 92-99.

  10. Bai W, Wang H, Fang R, Lin M, Qin Y, Han H, Cui J, Zhang R, Ma Y, Chen D, Zhang W, Wang L, Yu H*. Evaluating the effect of gestational diabetes mellitus on macrosomia based on the characteristics of oral glucose tolerance test. Clin Chim Acta. 2023 Apr 1;544:117362.

  11. Cui J, Zhang T, Zhang C, Xue Z, Chen D, Kong X, Zhao C, Guo Y, Li Z, Liu X, Duan J, Peng W, Zhou X, Yu H. Long-term exposure to low concentrations of polycyclic aromatic hydrocarbons and alterations in platelet indices: A longitudinal study in China. PLoS One. 2022 Nov 2;17(11):e0276944.

  12. Yao Qin, Jing Cui, Xiaoyan Ge, Yuling Tian,Hongjuan Han, Zhao Fan, Long Liu, Yanhong Luo,Hongmei Yu*.Hierarchical Multi-class Alzheimer's Disease Diagnostic Framework Using Imaging and Clinical Features. Frontiers in Aging Neuroscience, 2022.

  13. Sidan Du, Yao Qin, Min Han, Ying Huang, Jing Cui, Hongjuan Han, XiaoyanGe, Wenlin Bai, Xinnan Zhang & Hongmei Yu.Longitudinal Mediating Effect of Depression on the Relationship between Excessive Daytime Sleepiness and Activities of Daily Living in Parkinson's Disease. Clinical Gerontologist, 2022, Aug 11:1-10.

  14. Yifei Ma,Shujun Xu,Qi An,Mengxia Qin,Sitian Li,Kangkang Lu,Jiantao Li,Lijian Lei,Lu He,Hongmei Yu*, Jun Xie*.Coronavirus disease 2019 epidemic prediction in Shanghai under the “dynamic zero-COVID policy” using time-dependent SEAIQR model. Journal of biosafety and biosecurity,2022;4(2):105-113.

  15. Ying Huang,Sidan Du,Durong Chen,Yao Qin,Jing Cui,Hongjuan Han,Xiaoyan Ge,Wenlin Bai,Xinnan Zhang,Hongmei Yu*. The path linking excessive daytime sleepiness and activity of daily living in Parkinson’s disease: the longitudinal mediation effect of autonomic dysfunction. Neurological Sciences, 2022. Aug;43(8):4777-4784.

  16. Durong Chen, Fuliang Yi, Yao Qin, Jiajia Zhang, Xiaoyan Ge, Hongjuan Han, Jing Cui, Wenlin Bai,Yan Wu and Hongmei Yu∗ the Alzheimer’s Disease Neuroimaging Initiative. A Stacking Framework for Multi-Classification of Alzheimer’s Disease Using Neuroimaging and Clinical Features. Journal of Alzheimer’s Disease. 2022.87(4):1627-1636.

  17. XiaoyanGe, Kai Cui, Long Liu, Yao Qin, Jing Cui, Hongjuan Han, Yanhong Luo,HongmeiYu*.Screening and predicting progression from high‑risk mild cognitive impairment toAlzheimer’s disease. Scientific Reports. 2021, 11(1):17558.

  18. Xinnan Zhang, Yan Wu, Yao He, Xiaoyan Ge, Jing Cui, Hongjuan Han,Yanhong Luo, Long Liu, Zhixin Wang, Hongmei Yu*& the Alzheimer’s DiseaseNeuroimaging Initiative. Metrological properties of neuropsychological tests for measuring cognitive change in individuals with prodromal Alzheimer’s disease. Aging & Mental Health, 2022 Oct;26(10):1988-1996.

  19. Jing Cui,Yao Qin Yuling Tian,Xiaoyan Ge,Hongjuan Han,Zongfang Yang,Hongmei Yu*. Activities of daily living as a longitudinal moderator of the effect of autonomic dysfunction on anxiety and depression of Parkinson’s patients. Brain and Behavior, 2021. 2022 Oct;26(10):1988-1996.

  20. Hongjuan Han, Yao Qin, Xiaoyan Ge, Jing Cui, Long Liu, Yanhong Luo, Bei Yang, Hongmei Yu*. Risk Assessment during Longitudinal Progression of Cognition in Older Adults: A Community-based Bayesian Networks Model. Current Alzheimer Research. 2021. 18(3):232-242.

  21. Yao He, Yuling Tian, Hongjuan Han, Jing Cui, Xiaoyan Ge, Yao Qin, Yanhong Luo, Wenlin Bai,Hongmei Yu*. The path linking disease severity and cognitive function with quality of life in Parkinson’s disease: the mediating effect of activities of daily living and depression. Health and Quality of Life Outcomes, 2021, 19 (1):92.

  22. Xiaodou Tian , Yao Qin , Yuling Tian , Xiaoyan Ge , Jing Cui , Hongjuan Han , Long Liu, Hongmei Yu*. Identification of vascular dementia and Alzheimer's disease hub genes expressed in the frontal lobe and temporal cortex by weighted co-expression network analysis and construction of a protein-protein interaction. International Journal of Neuroscience. 10.1080/00207454.2020.1860966.

  23. Yan Wu, Xinnan Zhang, Yao He, Jing Cui, Xiaoyan Ge, Hongjuan Han, Yanhong Luo,Long Liu, Xuxia Wang, Hongmei Yu*,the Alzheimer's Disease Neuroimaging Initiative. Predicting Alzheimer's disease based on survival data and longitudinally measured performance on cognitive and functional scales. Psychiatry Research, 2020, 291:113201.

  24. Xiaoling Zhang, Hongjuan Han, Xiaoyan Ge, Long Liu, Tong Wang, Hongmei Yu*. Effect of n-3 long-chain polyunsaturated fatty acids on mild cognitive impairment: a meta-analysis of randomized clinical trials. European Journal of Clinical Nutrition, 2020, 74: 548–554.

  25. Yao Qin, Yuling Tian, Hongjuan Han, Long Liu, Xiaoyan Ge, Haihong Xue, Tong Wang, Liye Zhou, Ruifeng Liang,Hongmei Yu*,Alzheimer's Disease Neuroimaging Initiative. Risk classification for conversion from mild cognitive impairment to Alzheimer’s disease in primary care.Psychiatry Research, 2019, 278: 19-26. doi: 10.1016/j.psychres.2019.05.027

  26. Zongfang Yang, Yuling Tian, YingFan, LongLiu, Yanhong Luo, Liye Zhou, Hongmei Yu*. The mediating roles of caregiver social support and self-efficacy on caregiver burden in Parkinson’s disease.Journal of Affective Disorders, 2019, 256: 302-308. doi: 10.1016/j.jad.2019.05.064

  27. Zhixin Wang,Caiyun Ma,Hongjuan Han,Runlian He,Liye Zhou,Ruifeng Liang,Hongmei Yu*. Caregiver burden in Alzheimer’s disease: Moderation effects of social support and mediation effects of positive aspects of caregiving. International Journal of Geriatric Psychiatry, 2018,33:1198-1206.DOI: 10.1002/gps.4910

  28. Xuxia Wang, Xiaomeng Xu, Hongjuan Han, Runlian He, Liye Zhou, Ruifeng Liang,Hongmei Yu*.Using structural equation modeling to detect response shift in quality of life in patients with Alzheimer’s Disease.InternationalPsychogeriatrics, 2018. doi:10.1017/S1041610218000595

  29. Haihong Xue, Junwei Zhai, Runlian He, Liye Zhou, Ruifeng Liang, Hongmei Yu*.Moderating role of positive aspects of caregiving in the relationship between depression in persons with Alzheimer's disease and caregiver burden.Psychiatry Research, 2018, 261: 400-405.

  30. Haihong Xue, Qianqian Sun, Long Liu, Liye Zhou, Ruifeng Liang, Runlian He,Hongmei Yu*.Risk factors of transition from mild cognitive impairment to Alzheimer'sdisease and death: A cohort study.Comprehensive Psychiatry.2017, 78:91-97.

  31. Bei Yang, Hongmei Yu*, Min Xing, Runlian He,Ruifeng Liang, Liye Zhou.The relationship between cognition and depressivesymptoms, and factors modifying this association, inAlzheimer’s disease: a multivariate multilevel model.Archives of Gerontology and Geriatrics.2017,72:25-31.

  32. Hongmei Yu*, Caihong Gao, Yanbo Zhang, Runlian He, Liye Zhou, Ruifeng Liang. Trajectories of health-related quality of life during the natural history of dementia: a six-wave longitudinal study. International Journal of Geriatric Psychiatry. 2017, 32(9): 940-948.

  33. Hongmei Yu*,Xiaocheng Wang, Runlian He, Ruifeng Liang, Liye Zhou. Measuring the caregiver burden of caring for community-residing people with Alzheimer’s disease.PLoS ONE, 2015,10(7): e0132168.

  34. 张荣,张烁,余红梅*,刘龙.融合多模态影像的阿尔茨海默病多分类诊断模型.山西大学学报(自然科学版), 2021.

  35. 葛晓燕,韩红娟,罗艳虹,范炤,刘龙,王蕾,余红梅*.基于神经影像数据的阿尔茨海默病多分类诊断模型的研究进展与挑战.郑州大学学报, 2020, 55(1): 1-7.

  36. 王旭霞,贺润莲,吴燕萍,韩红娟,葛晓燕,刘龙,许晓萌,张岩波,余红梅*.纵向多分类项目反应理论评估阿尔茨海默病生命质量的反应转移.现代预防医学, 2019, 46(5): 844-848.

  37. 陈裔敏,王晶莹,韩红娟,余红梅*.基于Markov模型评价老年人认知损害合并抑郁的远期经济负担.中国卫生统计,2018,35(6):834-837.

  38. 刘龙,何航帜,王蕾,侯雅宣,萨建,王彤,余红梅*.基于OBE导向的医学统计学教学模式创新研究.中国卫生统计, 2018, 35(5): 793-795.

  39. 王志鑫,韩红娟,刘龙,余红梅*.轻度认知障碍老年人不同潜在类别的增长混合模型研究.中华疾病控制杂志, 2018, 22(9): 925-928.

  40. 刘龙,孙鹤立,赵春妮,罗艳虹,余红梅,张文平,郭峰,王彤*.医学毕业生就业现况及其满意度的影响因素分析.中国卫生统计, 2018, 35(3): 405-408.

  41. 20.段耀飞,宋泽婧,薛海红,樊莹,余红梅*.贝叶斯半参数多状态模型在老年人认知与抑郁关系研究中的应用.中国卫生统计, 2018, 35(2): 189-193.

  42. 樊莹,翟俊伟,侯彦,王俊英,段耀飞,薛海红,余红梅*.认知与抑郁对阿尔茨海默病患者照料者负担交互作用研究.中国公共卫生管理, 2017, 33(6): 737-741.

  43. 余红梅*.解析美国统计学会关于统计学检验和P值的声明.中国卫生统计, 2017, 34(4): 173-176.

  44. 许晓萌,孙倩倩,杨蓓,马彩云,余红梅*.特定转移Cox模型在阿尔茨海默病进程研究中的应用.中华疾病控制杂志, 2016, 20(9): 957-961.

  45. 杨蓓,邢敏,许晓萌,马彩云,余红梅*.阿尔茨海默病生命质量与日常行为能力的关系及其影响因素.中国公共卫生管理, 2016, 32(4): 427-430.

  46. 马彩云,孔盼盼,许晓萌,杨蓓,余红梅*.时间转换Markov模型在阿尔茨海默病进程研究中的应用.中国卫生统计, 2016, 33(4): 567-570.

  47. 王晶莹,王晓成,翟俊伟,宋泽婧,余红梅*.阿尔茨海默病经济负担水平及影响因素分析.中国公共卫生管理. 2016,32(1): 4-7.

  48. 宋泽婧,邢敏,王晶莹,翟俊伟,余红梅*.基于多元多水平模型的阿尔茨海默病认知与抑郁关系及其影响因素研究.中国卫生统计, 2016, 33(1): 9-11.