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赵海峰


赵海峰

医学博士,公共卫生与预防医学博士后、山西医科大学公共卫生学院营养与食品卫生学教研室教授、博士研究生导师

办公电话:0351-4135046

E-mail: haifengzhao75@sxmu.edu.cn,haifengzao75@163.com

受教育经历:

2006.9-2009.7北京大学,营养与食品卫生学专业,博士

1999.09-2002.07山西医科大学营养与食品卫生学专业,硕士

1994.09-1999.07山西医科大学预防医学系,学士

工作经历

2002.7-2004.12山西医科大学公共卫生学院营养与食品卫生学教研室 助教

2004. 12-2009.12山西医科大学公共卫生学院营养与食品卫生学教研室 讲师

2009.12-2016.12山西医科大学公共卫生学院营养与食品卫生学教研室 副教授

2016.12至今 山西医科大学营养与食品卫生学教研室 教授

2010.12-2012.12山西医科大学公共卫生与预防医学博士后

学习经历

2017.1-2018.1美国Brown University访问学者

学术任职

山西省营养学会秘书长兼副理事长、山西省专家学者协会医学分会理事、山西省优生科学协会环境与社会优生专业委员会常务委员、山西省科协科学传播首批专家、山西省人力资源和社会保障厅的“千人百县”高层次服务人才、山西省贫困地区义务教育阶段学生营养改善工作指导专家、中国营养学会营养流行病学分会委员、中国学生营养与健康促进会第八届理事会理事、中国老年学和老年医学学会营养食品分会委员、中国营养学会营养与组学技术分会委员、山西省粮油标准化技术委员会委员。

荣誉获奖

2019年山西省模范教师、2013年首届全国高校微课教学比赛山西省赛区三等奖、2011年山西医科大学第十一届“三育人”先进个人、2012年山西医科大学第十三届“育人杯”中青年教师教学基本功竞赛三等奖。此外,2010, 2012, 2013及2014, 2015,2018年指导的本科毕业论文获优秀论文奖。

教学情况

主要承担预防医学本科生的《营养与食品卫生学》理论、课间实习、生产实习的教学;此外还承担临床医学的《卫生学》、护理专业的《临床营养学》、本硕专业的《营养与疾病》、全校研究生临床营养学以及MPH研究生的《现代营养与食品卫生学》的教学。参编教材或著作4部,主持校教改课题1项(预防医学国家一流专业课题:预防医学本硕博贯通式人才培养模式的制度建设研究), 2项山西省大学生创新项目的指导教师。

研究领域

营养与疾病

代表性科研项目:

1.基于肠道菌群、脑组织葡萄糖代谢、线粒体-内质网偶联变化对茶多酚改善糖尿病并发认知功能障碍的作用和机制研究(81973047),2020.01-2023.12,55万。在研,主持。

2.国家自然科学基金项目面上项目,81472984,四种多酚类物质改善AD记忆的协同作用及对Aβ转运调节及NF-κB炎性反应抑制机制研究,2015.01-2018.12,75万元,已结题,主持。

3.国家博士后第51批二等资助,2012M510778,白藜芦醇改善AD大鼠记忆的NF-κB炎性信号调节机制研究,2012.06-2014.06,5万元,已结题,主持。

4.国家自然科学青年基金项目,81001245,白藜芦醇改善雌激素缺乏衰老大鼠记忆及NMDA受体介导的突触可塑性信号通路的机制研究,2011.01-2013.12,18万元,已结题,主持。

5.山西省高等学校科技开发项目,2010009,白藜芦醇预防原发性骨质疏松及机制研究,2010.05-2012.05,5万元,已结题,主持。

6.食物血糖生成指数的测定,5万,2016及2019年。已结题,主持。

7.预防医学国家一流专业课题:预防医学本硕博贯通式人才培养模式的制度建设研究。0.3万。在研,主持。

代表性论著:

1.Qian Yang, Yusen Zhang, Luping Zhang, Xuemin Li, Ruirui Dong, Chenmeng Song, Le Cheng, Mengqian Shi,Haifeng Zhao. Combination of tea polyphenols and proanthocyanidins Prevents Menopause-RelatedMemory Declinein Rats via Increased Hippocampal synaptic plasticity by inhibiting p38 MAPK and TNF-α pathway. Nutritional neuroscience, 2021,accepted.

2.The pentose phosphate pathway mediates hyperoxia-induced lung vascular dysgenesis and alveolar simplification in neonates. Jiannan Gong, Zihang Feng, Abigail L. Peterson1, Jennifer F. Carr, Xuexin Lu,Haifeng Zhao, Xiangming Ji, You-Yang Zhao, Monique E. De Paepe, Phyllis A. Dennery, Hongwei Yao. JCI insight, 2021. accepted.

3.Haifeng Zhao, Phyllis A. Dennery, Hongwei Yao. Metabolic reprogramming in the pathogenesis of chronic lung diseases, including BPD, COPD, and pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol, 2018, 314: L544–L554.

4.Haifeng Zhao, Qian Wang, Xuejiao Cheng, Xuemin Li, Na Li, Tiantian Liu, Jing Li, Qian Yang, Ruirui Dong, Yusen Zhang , Luping Zhang. Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Aβ1-42. Neuroscience, 2018, 379: 390-404.

5.HF. ZHAO, N. LI, Q. WANG, XJ. CHENG, X. M. LI, T. T. LIU. Reseratrol decreases the insoluble Aβ1-42 level in hippocampus and protects the integrity of the blood-brain barrier in AD rats. Neuroscience, 2015, 310 : 641-49.

6.Haifeng Zhao, Xuemin Li, Na Li, Tiantian Liu, Juan Liu, Ziwei Li, Huihui Xiao, Jinhui Li. Long-term resveratrol treatment prevents ovariectomy-induced osteopenia in rats without hyperplastic effects on the uterus. British Journal of Nutrition, 2014, 111, 836-846.

7.Haifeng Zhao, Qiao Niu, Xuemin Li, Tiantian Liu, Yunan Xu, Hao Han, Wanrong Wang, Ningxiu Fan, Qinqin Tian, Huifeng Zhang, Zelan Wang. Long-term resveratrol consumption protects ovariectomized rats chronically treated with D-galactose from developing memory decline without effects on the uterus.Brain research, 2012, 1467: 67-80.

8.H. F. ZHAO, Q. LI, Y. LI.Long-term ginsenoside administration prevents memory loss in aged female C57BL/6J mice by modulating the redox status and up-regulating the plasticity-related proteins in hippocampus. Neuroscience, 2011, 183:189–202.

9.Haifeng Zhao, Jiang Liang, Xuemin Li, Huanling Yu, Xiuhua Li, Rong Xiao.Folic acid and soybean isoflavone combined supplementation protects the post-neural tube closure defects of rodents induced by cyclophosphamide in vivo and in vitro. NeuroToxicology, 2010, 31:180-187.

10.Haifeng Zhao, Qiong Li, Xinrong Pei, Zhaofeng Zhang, Ruiyue Yang, JunboWang, Yong Li. Long-term ginsenoside consumption prevents memory loss in aged SAMP8 mice by decreasing oxidative stress and upregulating the plasticity-related proteins in hippocampus. Brain research, 2009, 1256:111-122.

11.Haifeng Zhao, Qiong Li, Zhaofeng Zhang, Xinrong Pei, Junbo Wang, Yong Li. Long-term ginsenoside administration prevents memory impairment in aged C57BL/6J mice by up-regulating the synaptic plasticity-related proteins in hippocampus. Behavioural Brain Research, 2009, 201:311-317.

12. Q.Li,H.F.ZHAO, Z.F.ZHANG, Z.G.LIU, X.R.PEI, J.B.WANG, Y.LI. Long-term Green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Aβ1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus. Neuroscience, 2009, 163 :741-749.

13. Q.Li,H.F.ZHAO, Z.F.ZHANG, Z.G.LIU, X.R.PEI, J.B.WANG, Y.LI. Long-term administration of Green tea catechins prevents age-related spatial learning and memory decline in C57BL/6J mice by regulating hippocampal CREB signaling cascade. Neuroscience, 2009, 159:1208-1215.

14. Qiong Li,Haifeng Zhao, Ming Zhao, Zhaofeng Zhang, Yong Li. Chronic green tea catechins administration prevents oxidative stress-related brain aging in C57BL/6J mice. Brain rearch, 2010, 1353, 28-35. 15. Zhaofeng Zhang, Ming Zhao, Qiong Li,Haifeng Zhao, Junbo Wang, Yong Li. Acetyl-L-carnitine inhibits TNF-a-induced insulin resistance via AMPK pathway in rat skeletal muscle cells. FEBS letters, 2009, 583:470-474.

16. R. Xiao, Jian T. Qiao,Hai F. Zhao. Sodium selenite induces apoptosis in cultured cortical neurons with special concomitant changes in expression of the apoptosis-related genes. NeuroToxicology, 2006, 27:478-484.

17. R. Xiao, Huan L. Yu,Hai F. Zhao. Developmental neurotoxicity role of cyclophosphamide on post-neural tube closure of rodents in vitro and in vivo. Int. J. Devl Neuroscience, 2007, 25:531-537.

18. Ruiyue Yang, Xinrong Pei, Junbo Wang, Zhaofeng Zhang,Haifeng Zhao, Qiong Li, Ming Zhao and Yong Li. Protective effect of amarine oligopeptide preparation from Chum Salmon (Oncorhynchus keta) on radiation-induced immune suppression in mice. J Sci Food Agric. 2010, 90(13):2241-8.

19.Wang J, Zhao M, Liang R, Zhang Z,Zhao H, Zhang J, Li T, Li Y. Whey peptides improve wound healing following caesarean section in rats. Br J Nutr. 2010, 104(11):1621-7.