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宁俊娅



姓名:宁俊娅

性别:女

出生年月:1992.04

政治面貌:中共党员

所在院系:山西医科大学基础医学院生理学系


学习工作经历

2015.09-2020.07山东大学,细胞生物学专业,理学博士

2020.09至今山西医科大学,讲师


研究方向

恶性肿瘤的发生发展与抗肿瘤药物的耐药性机制研究


发表论文及其他科研学术成果

1.Junya Ning, Zhaomin Lin, Xuan Zhao, Baoxiang Zhao*, Junying Miao*. Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells. Cell Death and Disease, 2019, 10(11):858. IF 2019: 6.304

2. Shi-Li Shen#,Jun-Ya Ning#, Xiao-Fan Zhang, Jun-Ying Miao, Bao-Xiang Zhao*.Through-bond energy transfer-based ratiometric fluorescent probe for the imaging of HOCl in living cells. Sensors and Actuators B: Chemical, 2017, 244:907-913. IF 2019: 7.100

3. Li-Jie Zhang#,Jun-Ya Ning#, Jun-Ying Miao, Jin-Ting Liu*, Bao-Xiang Zhao*. A new ratiometric fluorescent probe for detecting endogenous HClO in living cells. New Journal of Chemistry, 2018, 42(4):2989.

4. Qun Wei,Jun-Ya Ning, Xi Dai, Yuan-Di Gao, Le Su, Bao-Xiang Zhao*, Jun-Ying Miao*. Discovery of novel HSP90 inhibitors that induced apoptosis and impaired autophagic flux in A549 lung cancer cells. European Journal of Medicinal Chemistry, 2018, 145:551-558.

5. Wei Wang, Jun-Ya Ning, Jin-Ting Liu, Jun-Ying Miao, Bao-Xiang Zhao*. A mitochondria-targeted ratiometric fluorescence sensor for the detection of hypochlorite in living cells. Dyes and Pigments, 2019, 171:107708.

6. Huang M F, Chen L N,Ning J Y, et al. A new lipid droplets-targeted fluorescence probe for specific detection of SO2, derivatives in living cells [J]. Sensors and Actuators B: Chemical, 2018, 261:196-202.

7.He X, Lin Z,Ning J, Li N, Cui X, Zhao B, Hong F, Miao J. Promoting TTC4 and HSP70 interaction and translocation of annexin A7 to lysosome inhibits apoptosis in vascular endothelial cells. FASEB J. 2020 Sep;34(9):12932-12945.

苗俊英、赵宝祥、张尚立、宁俊娅;1,3,3-三甲基-2-苯并咪唑并吡啶乙烯基吲哚鎓碘化物在制备抗癌药物中的应用, 2019-04-12,中国, ZL201910294320.5.


科研项目

1.国家自然科学基金面上项目,31870831,膜联蛋白A7与葡萄糖调节蛋白94关联脂滴和细胞自噬的分子机制研究,2019/01-2022/12,在研,参与

2.国家自然科学基金面上项目,31871407,酯酶D调控其相互作用蛋白JAB1的去乙酰化及功能的机制研究,2019/01-2022/12,在研,参与