标志性成果 |
主持项目 1.国家自然科学基金青年项目,81802825,FAT1通过调控Wnt/β-catenin信号通路影响食管鳞癌细胞干性的机制研究,2019/01-2021/12,21万元,结题,主持 2.山西省自然科学研究面上项目,202203021211226,FAT1通过调控Hippo信号通路逆转食管鳞癌细胞耐药性的机制研究,2023/01-2025/12,10万元,在研,主持 3.山西省青年科技研究基金, 201701D221249, FAT1在食管鳞癌中的功能验证及机制研究, 2017/07-2019/12, 2万元, 结题, 主持 代表性论文 1.Xiaoling Hu, Yongping Cui*, FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer, Cancer Letters, 2017, 31;397:83-93. 2.Xiaoling Hu, Pengzhou Kong*, Xiaolong Cheng*, FAT1 inhibits cell migration and invasion by affecting cellular mechanical properties in esophageal squamous cell carcinoma, Oncology Reports,2018, 39(5): 2136-2146. 3.Guodong Li#, Xiaoling Hu#, Tongli Li*, Xiaohui Zhang*, C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance. Cell Mol Biol Lett. 2018, 20;23:26. 4.Yuanfang Zhai, Xiaoling Hu*, Xiaolong Cheng*, FAT1 downregulation enhances stemness and cisplatin resistance in esophageal squamous cell carcinoma, Molecular and Cellular Biochemistry, 2022, 477(12):2689-2702. 学术荣誉 2018 年获得山西省“三晋英才”优秀青年人才称号 |