科研项目 1. 山西省教育厅教改项目,J20230518,“金课”视域下《药物化学》混合式教学模式的研究与实践,2023/05-2025/05,1.0万元,在研,主持。 2. 山西医科大学校级教改项目,XJ2018064,《药用化学》教学改革与实践探索,2018/01-2019/12,0.3万元,结题,主持。 3. 山西省科技厅青年基金项目,20210302124586,黄芪注射液中植物初级代谢物的作用研究,2022/01-2024/12,4万,在研,主持。 4. 山西省科技厅重点研发项目,氯法齐明工艺改进与短疗程治疗多耐药肺结 核新适应症关键技术研究,2022/01-2025/01,8.0万元,合作单位第一负责人。 5. 太原市科技局太原市关键核心技术攻关“揭榜挂帅”项目,心脑血管药物舒血宁注射液高纯化原料分离和质量精准控制关键技术攻关,2023/06-2025/12,60.0万元,揭榜单位第一负责人。 发表论文 (1) Xiaolin Lu, Liqiu Yan, Xiaoxue Zhou, Tingli Qu*.Highly selective colorimetric determination of glutathione based on sandwich‑structured nanoenzymes composed of gold nanoparticle–coated molecular imprinted metal-organic frameworks. Microchimica Acta, 2024, 191:140. https://doi.org/10.1007/s00604-023-06167-2(2区,IF=5.700) (2) Liqiu Yan, Fangfang Liu, Yanyang Zhang, Erbing Wang &Tingli Qu*. Elucidating the active ingredients and potential anti-inflammatory mechanism of Qingwei Huanglian Wan. Journal of Liquid Chromatography & Related Technologies, 2023, DOI: 10.1080/10826076.2023.2297950.(4区,IF=1.300) (3) Tingli Qu, Yao Gao, Aiping Li, Zhenyu Li*, and Xuemei Qin*. Systems biology analysis of the effect and mechanism of total flavonoids of Astragali Radix against cyclophosphamide-induced leucopenia in mice. Journal of Pharmaceutical and Biomedical Analysis, 2021, 205: 114357.(3区,IF=3.935) (4) Erbing Wang, Teng Liu, Xiaolin Lu, Jinfang Xu, Qian Zheng, ZhengbaoZhao*, andTingli Qu*. Comparison of aerial parts of Astragalusmembranaceus and Astragali Radix based onchemical constituents and pharmacological effects. Food and Agricultural Immunology, 2019, 30(1): 1046-1066.(2区,IF=2.398) (5) Tingli Qu, Erbing Wang, Baofen Jin, Weiping Li, Ruiling Liu, and Zhengbao Zhao*. 5-Aminosalicylic acid inhibits inflammatory responses by suppressing JNK andp38 activity in murine macrophages. Immunopharmacology and Immunotoxicology, 2017,39(1): 45-53.(4区,IF=2.086) (6) Tingli Qu, Erbing Wang, Aiping Li, Guanhua Du, Zhenyu Li*, and Xuemei Qin*. NMR based metabolomic approach revealed cyclophosphamide-induced systematic alterations in a rat model. RSC Advances, 2016, 6(112): 111020-111030. (2区,IF=3.328) (7) Tingli Qu, Zhenyu Li*, Sijun Zhao, Aiping Li, and Xuemei Qin*. A metabonomic analysis reveals novel regulatory mechanism of Huangqi injection on leucopenia mice, Immunopharmacology and Immunotoxicology, 2016, 38(2): 113-123. (4区,IF=2.086) 申请专利 (1)发明名称:一种黄芪注射液1H-NMR指纹图谱的构建方法;发明人:李震宇,曲婷丽,张丽增,张松,秦雪梅;专利号:ZL 201410446123.8。 (2)发明名称:一种用于止嗽定喘祛痰的中药口服制剂;发明人:赵正保,曲婷丽,张西成,侯文林;专利号:ZL 200710163953.X。 (3)实用新型:一种中药提取装置;发明人:王二兵,曲婷丽;专利号:CN208212576U。 |