史晓晨
博士研究生
讲师
研究方向: 肌肉生长发育和再生机制研究;
邮箱: shixiaochen@sxmu.edu.cn
联系地址:山西省太原市新建南路56号
教育背景:
2011.09-2015.07 西北农林科技大学 动物科技学院 水产养殖专业 大学 农学学士
2015.09-2018.07 西北农林科技大学 动物科技学院 水产养殖专业 研究生 农学硕士
2018.09-2022.09 西北农林科技大学 动物科技学院 动物遗传育种与繁殖专业 农学博士
工作经历:
2022.12-至今 山西医科大学 转化医学研究中心 教师
(1) 国家自然科学基金委员会, 面上项目, 32070602, 利用CRISPR-Cas9技术构建ASGR1基因敲除猪作为人类动脉粥样硬化疾病模型的研究, 2021-01-01 至 2024-12-31, 58万元, 在研, 参与
(2) 国家自然科学基金委员会, 面上项目, 31772863, 内质网应激参与DHA促进草鱼脂肪细胞脂解过程的机制研究, 2018-01-01 至 2021-12-31, 61万元, 结题, 参与
1. Xiao Chen Shi#, Bo Xia#, Jian Feng Zhang, Rui Xin Zhang, Dan Yang Zhang, Huan Liu, Bao Cai Xie, Yong Liang Wang*, and Jiang Wei Wu*. "Optineurin promotes myogenesis during muscle regeneration in mice by autophagic degradation of GSK3β." PLoS biology 20, no. 4 (2022): e3001619. (中科院一区,top期刊,Nature Index期刊,IF=9.593)
2. Bao Cai Xie#, Xiao chen Shi#, Yan Li#, Bo Xia, Jia Zhou, Min Jie Du, Xiang Yang Xing, Liang Bai, En Qi Liu, Fernando Alvarez, Long Jin, Shao Ping Deng, Grant A. Mitchell, Deng Ke Pan*, Ming Zhou Li*, Jiang Wei Wu*. "Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans." PLoS genetics 17, no. 11 (2021): e1009891. (中科院二区,top期刊,Nature Index期刊,IF=6.020)
3. Xia Bo#, Xiao Chen Shi#, Bao Cai Xie#, Meng Qing Zhu, Yan Chen, Xin Yi Chu, Guo He Cai, Min Liu, Shi Zhen Yang, Grant A. Mitchell, Wei Jun Pang*, Jiang Wei Wu*. "Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice." PLoS biology 18, no. 3 (2020): e3000688. (中科院一区,top期刊,Nature Index期刊,IF=9.593)
4. Xiao Chen Shi, Ai Jin, Jian Sun, Jing Jing Tian, Hong Ji*, Li Qiao Chen, Zhen Yu Du. "The protein-sparing effect of α-lipoic acid in juvenile grass carp, Ctenopharyngodon idellus: effects on lipolysis, fatty acid β-oxidation and protein synthesis." British Journal of Nutrition 120, no. 9 (2018): 977-987. (中科院三区,IF=4.125)
5. Xiao Chen Shi, Jian Sun, Ai Jin, Hong Ji*, Hai Bo Yu, Yang Li, Xue Xian Li, Pin Liu, Chao Li, Ji Qin Huang. "Cytochrome P450 2AA molecular clone, expression pattern, and different regulation by fish oil and lard oil in diets of grass carp (Ctenopharyngodon idella)." Fish physiology and biochemistry 44, no. 4 (2018): 1019-1026. (中科院三区,IF=3.014)
6. Xiao Chen Shi, Ai Jin, Jian Sun, Zhou Yang, Jing Jing Tian, Hong Ji*, Hai Bo Yu, Yang Li, Ji Shu Zhou, Zhen Yu Du, Li Qiao Chen. "α-lipoic acid ameliorates n-3 highly-unsaturated fatty acids induced lipid peroxidation via regulating antioxidant defenses in grass carp (Ctenopharyngodon idellus)." Fish & shellfish immunology 67 (2017): 359-367. (中科院二区,top期刊,IF=4.622)
7. Xiao Chen Shi, Jian Sun, Zhou Yang, Xue Xian Li, Hong Ji*, Yang Li, Zhi Guang Chang, Zhen Yu Du, Li Qiao Chen. "Molecular characterization and nutritional regulation of carnitine palmitoyltransferase (CPT) family in grass carp (Ctenopharyngodon idellus)." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 203 (2017): 11-19. (中科院三区,IF=2.495)
8. Xiao Chen Shi,et al., " Optineurin (OPTN) interacts with JUP/PI3K complex in the PI3K/AKT/mTOR pathway to prevent muscle atrophy." PLoS biology (In preparation)