工作经历：                                                                                  
（1）2008/10 -今      山西医科大学  转化医学研究中心            教授    博士生导师
（2）2008/08 -2018/10 山西医科大学  细胞生理学省部共建教育部重点实验室        教授    博士生导师                    
（3）2008/09-2009/12  山西医科大学  基础医学院细胞生物学      教授    博士生导师
（4）2003/09-2008/09  山西医科大学  基础医学院细胞生物学      副教授        硕导
（5）1997/09-2003/08  山西医科大学  基础医学院生物化学与分子生物学        讲师
教育背景：                                                                              
(1)2017/08-2017/12，University of Virginia                                       高级访问学者
(2)2004/12-2009/12，H. Lee Moffitt Cancer Center (NCI at USF)           博士后
(3)2004/07-2004/12，University of Michigan                                       博士后
(4)2000/9 - 2003/7   中国医学科学院/中国协和医科大学，肿瘤医院/肿瘤研究所，肿瘤学博士，导师: 陆士新院士  詹启敏院士
(5)1994/9 - 1997/7   山西医科大学公共卫生与预防医学， 硕士，导师: 张喜忠
(6)1989/9 - 1994/7   山西医学院，预防医学，学士
                                                     
围绕我国特色高发恶性肿瘤食管癌，联合食管癌高发区（山西、新疆、潮汕等地区）肿瘤病理学、肿瘤外科学、肿瘤放化疗等临床研究人员，组建了“消化系统恶性肿瘤防治山西省科技创新重点团队”、“食管癌发病机理及转化研究山西省重点实验室”，聚焦我国高发区食管癌遗传变异分析、分子标记物筛查及驱动基因分子调控网络研究。聚焦我国高发区食管癌遗传变异分析、分子标记物筛查及驱动基因分子调控网络研究，搭建了我国食管鳞癌多组学数据库，在国际上率先从克隆进化角度揭示了食管鳞癌高异质性，揭示了食管鳞癌 DNA 甲基化特征全貌，鉴定了一批与食管鳞癌发生发展及转移、预后显著相关的基因及信号通路，揭示了食管鳞癌免疫逃逸的可能机制；基于多个独立队列的大样本多组学测序数据，鉴定了我国食管鳞癌的临床分子分型标记物，强有力地预测了患者的预后生存，提出了我国人群食管鳞癌分子分型的建议标准；基于食管鳞癌患者病理图像及影像组学数据，开展了病理图像特征、影像组学特征与生物标志物的关联研究，系统解析病理图像及影像组学在食管鳞癌疗效与预后评估、新治疗靶点和食管鳞癌发生发展的生物机制，为建立融入病理图像及影像组学医学人工智能分析平台，促进精准化个性化的智能医疗应用和发展奠定了坚实的基础。

1.国家自然科学基金联合基金重点项目，U21A20372，基于多组学整合分析的食管下段癌分子分型及不同亚型调控机制的研究，崔永萍，山西医科大学承担，260万元，2022.01-2025.12，在研，主持。
2.国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项，2016YFC1302100，细胞稳态破坏导致肿瘤发生的分子机制，崔永萍，山西医科大学承担，80万元，2016/09-2020/12，已结题，子课题负责人。
3.国家自然科学基金重点项目，81330063，食管鳞癌异质性及耐药机制的多组学贯穿分析研究，崔永萍，山西医科大学承担，290万元，2014/01-2018/12，结题，主持。
4.863计划生物和医药技术领域，SS2014AA020601，食管癌多维度分子网络研究，崔永萍，山西医科大学承担，100万元，2014/1-2016/12，结题，子课题负责人。
5.教育部重点项目，213005A，食管癌耐药机制的多组学贯穿分析研究，崔永萍，山西医科大学承担，50万元，2014/01-2015/12，结题，主持。
6.国家自然科学基金面上项目，81272189，癌基因BRAFV600E导致两极纺锤体结构及定位异常分子机制，崔永萍，山西医科大学承担，85万元，2013/01-2016/12，结题，主持。
7.国家自然科学基金面上项目，30971518，食管癌相关基因2抑制肿瘤细胞侵袭迁移的分子机理，崔永萍，山西医科大学承担，30万元，2010/01-2012/12，结题、主持。
8.国家自然科学基金面上项目，30872932，癌基因B-RAFV600E过度激活纺锤体检测点功能及导致中心体复制异常的分子机制，崔永萍，山西医科大学承担，34万元，2009/01-2011/12，结题，主持。
9.国家自然科学基金面上项目，30500588，食管癌相关基因2功能和结构的研究，崔永萍，山西医科大学承担，25万元，2006/01-2008/12，结题，主持。
10.教育部“新世纪优秀人才支持计划”， NCET-10-0872，食管癌相关基因编码蛋白研究，崔永萍，山西医科大学承担，50万元，2010/01-2012/12，结题，主持。
11.高等学校博士学科点专项科研基金，20121417110004，ECRG2基因在食管癌等常见恶性肿瘤中的变异、功能分析及临床意义评价，崔永萍，山西医科大学承担，12万元，2012/01-2014/12，结题，主持。
12.教育部留学回国人员科研启动基金，教外司留[2009]8号，癌基因B-RAF在肿瘤细胞染色体不稳定性中的作用及机制研究，崔永萍，山西医科大学承担，2.5万元，2010/01-2011/12，结题，主持。
13.山西省高等教育“1331工程”重点创新团队提质增效建设计划项目，消化系统肿瘤癌变机制及转化研究骨干创新团队建设项目，崔永萍，山西医科大学承担，80万元，2022/01-2023/12,在研，主持。                                          
14.中央引导地方科技发展专项资金项目（YDZX20191400004521），山西省食管癌多组学数据库共享平台，崔永萍，山西医科大学承担，100万元，2019/02-2021/02，结题，项目负责人。
15.“1331工程”重点学科建设计划，“1331工程”重点学科建设-基础医学，晋教科[2017]6号，崔永萍，山西医科大学承担，650万元，结题，子方向带头人。
16.食管癌发病机理及转化研究山西省重点实验室，晋科函[2017]91号，崔永萍，山西医科大学承担，20万，2017.07-2019.06，结题，实验室主任，主持。
17.山西省科技创新团队项目，201605D131045-16，消化系统恶性肿瘤防治创新重点团队，崔永萍，山西医科大学承担，15万元，2016/07-2019/06，结题，团队带头人，主持。
18.山西省青年“三晋学者”，晋教研2016[7]号，崔永萍，山西医科大学承担，50万元，2016-2020，结题，主持。
19.山西省“1331工程”重点实验室、工程（技术）研究中心、产业技术创新研究院（战略联盟）建设计划，食管癌发病机理及转化研究山西省“1331工程”重点实验室，崔永萍，山西医科大学承担，100万元，2017/9-2020/12，结题，团队带头人，主持。
20.高等学校“优势学科攀升计划”， 消化系统恶性肿瘤防治，崔永萍，山西医科大学承担，400万元，2016/01-2020/12，结题，团队带头人，主持。
21.山西省高等学校优秀创新团队项目，2015-0101，2015年度山西省高等学校优秀创新团队，崔永萍，山西医科大学承担，100万元，2016/01-2018/12，结题，团队带头人，主持。
22.山西省重点研发计划，2016010303100005，食管鳞癌基因组学研究及其在临床早期诊断、耐药分型和预后预测中的应用，崔永萍，山西医科大学承担，20万元，2016/01-2018/12，结题，主持。
23.山西省回国留学人员科研资助重点项目，2015-重点3，食管癌分子分型及耐药特意分子标记的筛选鉴定，崔永萍，山西医科大学承担，30万元，2015/01-2018/12，在研，主持。
24.山西省重点学科建设专项经费，晋财教[2012]143号，恶性肿瘤发病机制、早期诊断标记物及靶向治疗，崔永萍，山西医科大学承担，380万元，2013/01-2015/12，结题，主持。
25.山西省高等学校中青年拔尖创新人才，晋教科[2014]7号，消化系统恶性肿瘤防治创新团队，崔永萍，山西医科大学承担，20万元，2014/01-2016/12，结题，主持。

1.    Zhihua Liu; Yahui Zhao; Pengzhou Kong; Yuhao Liu; Jing Huang; Enwei Xu; Wenqing Wei; Guangyu Li; Xiaolong Cheng; Liyan Xue; Yi Li; Hongyan Chen; Shuqing Wei; Ruifang Sun; Heyang Cui; Yongsheng Meng; Meilin Liu; Yang Li; Riyue Feng; Xiao Yu; Rui Zhu; Yenan Wu; Lei Li; Bin Yang; Yanchun Ma; Jiawei Wang; Wenjie Zhu; Dongjie Deng; Yanfeng Xi; Fang Wang; Hongyi Li; Shiping Guo; Xiaofei Zhuang; Xiaoyue Wang; Yuchen Jiao; Yongping Cui*; Qimin Zhan* (2022), Integrated Multi-omics Profiling Yields a Clinically-Relevant Molecular Classification for Esophageal Squamous Cell Carcinoma, Cancer Cell, In press.                      IF=38.585
2.    Heyang Cui#, Yong Zhou#, Fang Wang#, Caixia Cheng#, Weimin Zhang#, Ruifang Sun#, Ling Zhang#, Yanghui Bi, Min Guo, Yan Zhou, Xinhui Wang, Jiaxin Ren, Ruibing Bai, Ning Ding, Chen Cheng, Longlong Wang, Xuehan Zhuang, Mingwei Gao, Yongjia Weng, Yueguang Wu, Huijuan Liu, Shuaicheng Li, Shubin Wang, Xiaolong Cheng, Yongping Cui*, Zhihua Liu*& Qimin Zhan*. Characterization of Somatic Structural Variations in 528 Chinese individuals with Esophageal Squamous Cell Carcinoma. Nature Communications.2022 Oct 22;13(1):6296. doi: 10.1038/s41467-022-33994-3.
IF= 17.694
3.    Hongyi Li#, Shaojie Wang#, Xiubo Li, Yongjia Weng, Dinghe Guo, Pengzhou Kong, Caixia Cheng, Yanqiang Wang, Ling Zhang, Xiaolong Cheng*, Yongping Cui*. CDCA7 promotes TGF-β-induced epithelial-mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC. Cancer Sci. 2022 Sep 2.doi: 10.1111/cas.15560.              
IF= 6.518
4.    Yingzhen Gao#, Liuyi Shen#, Tianyue Dong#, Xin Yang, Heyang Cui, Yanlin Guo, Yanchun Ma, Pengzhou Kong, Xiaolong Cheng, Ling Zhang* and Yongping Cui*.An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma. Journal of Translational Medicine. 2022 Jun 25;20(1):285.    
IF= 8.440
5.    Fang Wang#, Caixia Cheng#, Xinhui Wang, Fei Chen, Hongyi Li, Yan Zhou, Yanqiang Wang, Xiaoling Hu, Pengzhou Kong,Ling Zhang, Xiaolong Cheng* and Yongping Cui*. Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma. Cell Death Discovery. 2022 Apr 8;8(1):182.      IF= 7.109
6.    Binbin Zou, Dinghe Guo , Pengzhou Kong, Yanqiang Wang, Xiaolong Cheng*, Yongping Cui*. Integrative Genomic Analyses of 1,145 Patient Samples Reveal New Biomarkers in Esophageal Squamous Cell Carcinoma. Frontiers in Molecular Biosciences. 2022 Jan 21;8:792779.                                  IF= 6.113
7.    Chen Cheng, Heyang Cui, Huijuan Liu, Yueguang Wu, Ning Ding, Yongjia Weng, Weimin Zhang* and Yongping Cui*.Role of Epidermal Growth Factor Receptor-Specific CAR-T Cells in the Suppression of Esophageal Squamous Cell Carcinoma. Cancers. 2022, 14, 6021.                                 IF=6.575
8.    Li Y#, Yang B, Ma Y, Peng X, Wang Z, Sheng B, Wei Z, Cui Y*, Liu Z*；Phosphoproteomics reveals therapeutic targets of esophageal squamous cell carcinoma. Signal Transduct Target Ther. 2021 Nov 12;6(1):381. doi: 10.1038/s41392-021-00682-5.                                       IF=38.1
9.    Hongyi Li H# ; Yongjia Weng#; Shaojie Wang; Fang Wang; Yanqiang Wang; Pengzhou Kong; Ling Zhang; Caixia Cheng; Heyang Cui; Enwei Xu; Shuqing Wei; Dinghe Guo; Fei Chen; Yanghui Bi; Yongshen Meng; Xiaolong Cheng*; Yongping Cui* ; CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma, Front Oncol. 2021, 11: 734655.              IF= 6.244
10.    Heyang Cui#, Yongjia Weng, Ning Ding, Chen Cheng, Longlong Wang, Yong Zhou, Ling Zhang, Yongping Cui*, Weimin Zhang*. Autophagy-Related Three-Gene Prognostic Signature for Predicting Survival in Esophageal Squamous Cell Carcinoma. Front Oncol. 2021 Jul 15;11:650891. doi: 10.3389/fonc.2021.650891.      IF= 6.244
11.    Yongping Cui#, Hongyan Chen#, Ruibin Xi#, Heyang Cui#, Yahui Zhao#, Enwei Xu#, Ting Yan, Xiaomei Lu, Furong Huang, Pengzhou Kong, Yang Li, Xiaolin Zhu, Jiawei Wang, Wenjie Zhu, Jie Wang, Yanchun Ma, Yong Zhou, Shiping Guo,Ling Zhang, Yiqian Liu, Bin Wang, Yanfeng Xi, Ruifang Sun, Xiao Yu, Yuanfang Zhai, Fang Wang, Jian Yang, Bin Yang, Caixia Cheng, Jing Liu, Bin Song, Hongyi Li, Yi Wang, Yingchun Zhang, Xiaolong Cheng, Qimin Zhan*, Yanhong Li*, Zhihua Liu*. Whole-genome Sequencing of 508 Patients Identifies Key Molecular Features Associated With Poor Prognosis in Esophageal Squamous Cell Carcinoma. Cell Res. 2020, 30(10):902-913. doi: 10.1038/s41422-020-0333-6.                                      IF= 46.378
12.    Zhang, Z.#, Zhou, L., Xie, N., Nice, E. C., Zhang, T., Cui, Y., & Huang, C. . Overcoming cancer therapeutic bottleneck by drug repurposing. Signal Transduction and Targeted Therapy, 5(1).(2020) doi:10.1038/s41392-020-00213-8        
IF=38.1
13.    Ling Zhang#, Yingzhen Gao#, Xiaojuan Zhang#, Min Guo#, Jie Yang#, Heyang Cui, Pengzhou Kong, Xia Niu, Yanghui Bi, Jing Xu, Ting Yan, Yanchun Ma, Jian Yang, Yu Qian, Fang Wang, Hongyi Li, Feng Liu, Xiaolong Cheng, Yongping Cui.TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2. Theranostics. 2020, 10(24):11339-11358.                      
IF= 8.579
14.    Pengzhou Kong#, Enwei Xu#, Yanghui Bi#, Xiaoqin Xu#, Xue Liu#,Bin Song, Ling Zhang, Caixia Cheng, Ting Yan, Yu Qian, Jian Yang, Yanchun Ma, Heyang Cui, Yuanfang Zhai, Binbin Zou, Xiangchen Liu, Yikun Cheng, Shiping Guo, Xiaolong Cheng*, Yongping Cui*. Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC. Theranostics. 2020, 10(4):1798-1813.                         IF= 8.579
15.    Yanghui Bi#, Shixing Guo#, Xiaoqin Xu#, Pengzhou Kong#, Heyang Cui#, Ting Yan#, Yanchun Ma#, Yikun Cheng#, Yunqing Chen#, Xue Liu, Ling Zhang, Caixia Cheng, Enwei Xu, Yu Qian , Jian Yang , Bin Song, Hongyi Li, Fang Wang , Xiaoling Hu, Xiangchen Liu , Xia Niu , Yuanfang Zhai, Jing Liu , Yaoping Li , Xiaolong Cheng*, Yongping Cui*. Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma. Cell Death & Disease. 2020, 11(4):296.                              IF=6.304
16.    Yu Qian#, Xiao Liang# , Pengzhou Kong# , Yikun Cheng , Heyang Cui, Ting Yan, Jinghao Wang, Ling Zhang, Yiqian Liu, Shiping Guo, Xiaolong Cheng*, Yongping Cui*.Elevated DHODH expression promotes cell proliferation via stabilizing β-catenin in esophageal squamous cell carcinoma. Cell Death and Disease. 2020，11(10):862            
IF=6.304
17.    Jian Yang#，Tianyi Guo#，Xiao Liang#，Yuanfang Zhai，Yikun Cheng, Hui Sun, Yongping Cui*, Xiaolong Cheng*. Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6. Ecotoxicology and Environmental Safety. 2020, 205:111146.                                                     IF=4.872
18.    Ting Yan#, Heyang Cui#, Yong Zhou#, Bin Yang#, Pengzhou Kong#, Yingchun Zhang#, Yiqian Liu, Bin Wang, Yikun Cheng, Jiayi Li, Shixing Guo, Enwei Xu, Huijuan Liu, Caixia Cheng, Ling Zhang, Ling Chen, Xiaofei Zhuang, Yu Qian, Jian Yang, Yanchun Ma, Hongyi Li, Fang Wang, Jing Liu, Xuefeng Liu, Dan Su, Yan Wang, Ruifang Sun, Shiping Guo, Yaoping Li, Xiaolong Cheng, Zhihua Liu, Qimin Zhan* & Yongping Cui*. Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma. Nature Communications. 2019, 10(1):1670. doi: 10.1038/s41467-019-09255-1.                                     IF= 17.694
19.    Yanghui Bi#, Pengzhou Kong#, Ling Zhang#, Heyang Cui#, Xiaoqin Xu#, Feiyun Chang#, Ting Yan, Jiayi Li, Caixia Cheng, Bin Song, Xia Niu, Xiangchen Liu, Xue Liu, Enwei Xu, Xiaoling Hu, Yu Qian, Fang Wang, Hongyi Li, Yanchun Ma, Jian Yang, Yiqian Liu, Yuanfang Zhai, Yi Wang, Yingchun Zhang, Haiyan Liu, Jing Liu, Jintao Wang*, Yongping Cui, Xiaolong Cheng*. EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma. J Cancer. 2019, 10(22):5413-5426.    IF= 3.182
20.    Wei Gao#, Chunming Zhang#, Wenqi Li#, Huizheng Li#, Jiangwei Sang#, Qinli Zhao, Yunfeng Bo, Hongjie Luo, Xiwang Zheng, Yan Lu, Yong Shi, Dongli Yang, Ruiping Zhang, Zhenyu Li, Jiajia Cui, Yuliang Zhang, Min Niu, Jun Li, Zhongqiang Wu, Huina Guo, Caixia Xiang, Juan Wang, Juan Hou, Lu Zhang, Rick F. Thorne*, Yongping Cui*, Yongyan Wu*, Shuxin Wen*, Binquan Wang*. Promoter Methylation-Regulated miR-145-5p Inhibits Laryngeal Squamous Cell Carcinoma Progression by Targeting FSCN1. Molecular Therapy. 2019, 27(2):365-379.                     IF= 8.402
21.    Ma Yanchun#, Wang Yi#, Wang Lu, Qian Yu, Yang Jian, Kong Pengzhou, Yan Ting, Li Hongyi, Wang Fang, Cheng Xiaolong, Cui Yongping*. Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway. Eur J Pharmacol. 2019, 851:43-51.                                 IF= 3.170
22.    Jie Yang, Pengzhou Kong, Jian Yang, Zhiwu Jia, Xiaoling Hu, Zianyi Wang, Heyang Cui, Yanghui Bi, Yu Qian, Hongyi Li, Fang Wang, Bin Yang, Ting Yan, Yanchun Ma, Ling Zhang, Caixia Cheng, Bin Song, Yaoping Li, Enwei Xu, Haiyan Liu, Wei Gao, Juan Wang, Yiqian Liu, Yuanfang Zhai, Lu Chang, Yi Wang, Yingchun Zhang, Ruyi Shi, Jing Liu, Qi Wang, Xiaolong Cheng, Yongping Cui*. High TSTA3 Expression as a Candidate Biomarker for Poor Prognosis of Patients With ESCC. Technol Cancer Res Treat. 2018, 17:1533033818781405.                                 IF= 1.464
23.    Yike Li#, Yanyan Zhang#, Shuaishuai Xiao , Pengzhou Kong, Caixia Cheng, Ruyi Shi, Fang Wang, Ling Zhang, Juan Wang, Zhiwu Jia, Shuai Wu, Yun Liu, Jiansheng Guo, Xiaolong Cheng, Yongping Cui*, Jing Liu*. Mps1 is associated with the BRAFV600E mutation but does not rely on the classic RAS/RAF/MEK/ERK signaling pathway in thyroid carcinoma. Oncol Lett. 2018, 15(6):9978-9986.                  IF= 1.871
24.    Xiaoling Hu#, Yuanfang Zhai#, Pengzhou Kong#, Heyang Cui#, Ting Yan, Jian Yang, Yu Qian, Yanchun Ma, Fang Wang, Hongyi Li, Caixia Cheng, Ling Zhang, Zhiwu Jia, Yaoping Li, Bin Yang, Enwei Xu, Juan Wang, Jie Yang, Yanghui Bi, Lu Chang, Yi Wang, Yingchun Zhang, Bin Song, Guodong Li, Ruyi Shi, Jing Liu, Mingsheng Zhang, Xiaolong Cheng, Yongping Cui*. FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer. Cancer Letters. 2017; 397:83-93.                                          IF=6.491
25.    Bin Yang#, Ting Yan#, Heyang Cui#, Enwei Xu#, Yanchun Ma#, Caixia Cheng#, Ling Zhang, Pengzhou Kong, Fang Wang, Yu Qian, Jian Yang, Yaoping Li, Hongyi Li, Yanghui Bi, Xiaoling Hu, Juan Wang, Bin Song, Jie Yang, Wei Gao, Jing Liu, Binbin Zou, Ruyi Shi, Yanyan Zhang, Haiyan Liu, Yiqian Liu, Yuanfang Zhai, Lu Chang, Yi Wang, Yingchun Zhang, Zhiwu Jia, Xing Chen, Yanfeng Xi, Guodong Li, Jianfang Liang, Jiansheng Guo, Shiping Guo, Rongsheng Zhang, Xiaolong Cheng, Yongping Cui*. The macro-evolutionary events in esophageal squamous cell carcinoma. Oncotarget. 2017, 8(68):112770-112782.                             IF= 6.359
26.    Shan P#, Fan G#, Sun L#, Liu J, Wang W, Hu C, Zhang X, Zhai Q, Song X, Cao L, Cui Y, Zhang S*, Wang C*. SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport. Curr Biol. 2017, 27(15):2271-2284.e5.           IF= 9.193
27.    Caixia Cheng#, Yong Zhou#, Hongyi Li#, Teng Xiong#, Shuaicheng Li#, Yanghui Bi#, Pengzhou Kong, Fang Wang, Heyang Cui, Yaoping Li, Xiaodong Fang, Ting Yan, Yike Li, Juan Wang, Bin Yang, Ling Zhang, Zhiwu Jia, Bin Song, Xiaoling Hu, Jie Yang, Haile Qiu, Gehong Zhang, Jing Liu, Enwei Xu, Ruyi Shi, Yanyan Zhang, Haiyan Liu, Chanting He, Zhenxiang Zhao, Yu Qian, Ruizhou Rong, Zhiwei Han, Yanlin Zhang, Wen Luo, Jiaqian Wang, Shaoliang Peng, Xukui Yang, Xiangchun Li, Lin Li, Hu Fang, Xingmin Liu, Li Ma, Yunqing Chen, Shiping Guo, Xing Chen, Yanfeng Xi, Guodong Li, Jianfang Liang, Xiaofeng Yang, Jiansheng Guo, JunMei Jia, Qingshan Li, Xiaolong Cheng, Qimin Zhan*, Yongping Cui*. Whole-genome Sequencing Reveals Diverse Models of Structural Variations In Esophageal Squamous Cell Carcinoma. American Journal of Human Genetics. 2016, 98(2):256-74. doi: 10.1016/j.ajhg.2015.12.013.
Faculty of 1000 Recommends as one of the Most Important Article      IF= 10.931
28.    Caixia Cheng#, Heyang Cui#, Ling Zhang#, Zhiwu Jia#, Bin Song#, Fang Wang#, Yaoping Li, Jing Liu, Pengzhou Kong, Ruyi Shi, Yanghui Bi, Bin Yang, Juan Wang, Zhenxiang Zhao, Yanyan Zhang, Xiaoling Hu, Jie Yang, Chanting He, Zhiping Zhao, Jinfen Wang,Yanfeng Xi, Enwei Xu, Guodong Li, Shiping Guo, Yunqing Chen, Xiaofeng Yang, Xing Chen, Jianfang Liang, Jiansheng Guo, Xiaolong Cheng, Chuangui Wang, Qimin Zhan*, Yongping Cui*, Genomic analyses reveal FAM84B and NOTCH pathway relate to the progression of esophageal squamous cell carcinoma. GigaScience. 2016, 5:1. DOI 10.1186/s13742-015-0107-0                                        IF= 7.463
29.    Sun L#, Fan G#, Shan P#, Qiu X, Dong S, Liao L, Yu C, Wang T, Gu X, Li Q, Song X, Cao L, Li X, Cui Y, Zhang S*, Wang C*. Regulation of energy homeostasis by the ubiquitin-independent REGγ proteasome. Nat Commun. 2016,7:12497.     IF= 11.47
30.    Bin Song#, Heyang Cui#, Yaoping Li#, Caixia Cheng#, Bin Yang#, Fang Wang#, Pengzhou Kong#, Hongyi Li, Ling Zhang, Zhiwu Jia, Yanghui Bi, Jiaqian Wang, Yong Zhou, Jing Liu, Juan Wang, Zhenxiang Zhao, Yanyan Zhang, Xiaoling Hu, Ruyi Shi, Jie Yang, Haiyan Liu, Ting Yan, Yike Li, Enwei Xu, Yu Qian, Yanfeng Xi, Shiping Guo, Yunqing Chen, Jinfen Wang, Guodong Li, Jianfang Liang, Junmei Jia, Xing Chen, Jiansheng Guo, Tong Wang, Yanbo Zhang, Qingshan Li Chuangui Wang, Xiaolong Cheng, Qimin Zhan*, Yongping Cui*. Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China. Oncotarget. 2016, 7(3):3599-613. doi: 10.18632/oncotarget.6120.                                          IF=5.168
31.    Fan G#, Sun L#, Shan P#, Zhang X, Huan J, Zhang X, Li D, Wang T, Wei T, Zhang X, Gu X, Yao L, Xuan Y, Hou Z, Cui Y, Cao L, Li X, Zhang S*, Wang C*. Loss of KLF14 triggers centrosome amplification and tumorigenesis. Nat Commun. 2015;6:8450. doi: 10.1038/ncomms9450.                                            IF= 11.47
32.    Ling Zhang#, Yong Zhou#, Caixia Cheng#, Heyang Cui#, Le Cheng#, Pengzhou Kong#, Jiaqian Wang#, Yin Li#, Wenliang Chen, Bin Song, Fang Wang, Zhiwu Jia, Lin Li, Yaoping Li, Bin Yang, Jing Liu, Ruyi Shi, Yanghui Bi, Yanyan Zhang, Juan Wang, Zhenxiang Zhao, Xiaoling Hu, Jie Yang, Hongyi Li, Zhibo Gao, Gang Chen, Xuanlin Huang, Xukui Yang, Shengqing Wan, Chao Chen, Bin Li, Yongkai Tan, Longyun Chen, Minghui He, Sha Xie, Xiangchun Li, Xuehan Zhuang, Mengyao Wang, Zhi Xia, Longhai Luo, Jie Ma, Bing Dong, Jiuzhou Zhao, Yongmei Song, Yunwei Ou, Enming Li, Liyan Xu, Jinfen Wang Yanfeng Xi Guodong Li Enwei Xu Jianfang Liang, Xiaofeng Yang, Jiansheng Guo, Xing Chen, Yanbo Zhang, Qingshan Li, Lixin Liu, Yingrui Li, Xiuqing Zhang, Huanming Yang, Dongxin Lin, Xiaolong Cheng, Yongjun Guo, Jun Wang, Qimin Zhan*, Yongping Cui*. Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. American Journal of Human Genetics. 2015, 96(4):597-611.
Best Papers of AJHG 2014 to 2015                        IF= 10.931
33.    J Liu#, X Cheng#, Y Zhang#, S Li, H Cui, L Zhang, R Shi, Z Zhao, C He, C Wang, H Zhao, C Zhang, HA Fisk, TM Guadagno, Y Cui*. Phosphorylation of Mps1 by BRAFV600E Prevents Mps1 Degradation and Contributes to Chromosome Instability in Melanoma. Oncogene. 2013, 32(6):713-23                           IF= 8.559
34.    Ling Zhang#, Ruyi Shi#, Chanting He#, Caixia Cheng, Bin Song, Heyang Cui, Yanyan Zhang, Zhiping Zhao, Yanghui Bi, Xiaofeng Yang, Xiaoping Miao, Jiansheng Guo, Xing Chen, Jinfen Wang, Yaoping Li, Xiaolong Cheng, Jing Liu*, Yongping Cui*. Oncogenic B-RafV600E abrogates the AKT/B-Raf/Mps1 interaction in melanoma cells. Cancer Letters. 2013, 337:125–132.                                 IF= 5.990                                      
35.    Yongping Cui#, Meghan K#. Borysova, Joseph O. Johnson, Thomas M. Guadagno*. Oncogenic B-RafV600E Induces Spindle Abnormalities, Supernumerary Centrosomes, an Aneuploidy in Human Melanocytic Cells. Cancer Research. 2010, 70(2): 675-684.                                                          
IF= 9.329
36.    Xiaolong Cheng#, Shih-Hsin Lu, Yongping Cui*. ECRG2 regulates ECM degradation and uPAR/FPRL1 pathway contributing cell invasion/migration. Cancer Letters. 2010, 290(1):87-95.                                                   IF= 5.990
37.    Yongping Cui#, Xiaolong Cheng, Ce Zhang, Yanyan Zhang, Shujing Li, Chuangui Wang, Thomas M*. Guadagno. Degradation of the Human Mitotic Checkpoint Kinase Mps1 is Cell-cycle Regulated by APC/cCdc20 and APC/cCdh1 Ubiquitin Ligases. Journal of Biological Chemistry. 2010, 285(43):32988-998.             IF= 5.808
38.    Xiaolong Cheng#, Zheng Shen, Litian Yin, Shih-Hsin Lu, Yongping Cui*. ECRG2 regulates cell migration invasion through urokinase-type plasmin activator receptor (uPAR)/beta1 integrin pathway. Journal of Biological Chemistry. 2009, 284(45): 30897-30906.                                                   IF= 5.808
39.    Cui Y#, Guadagno TM*. B-RafV600E signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells. Oncogene. 2008, 27, 3122-3133.                                                     IF= 8.559
40.    Xiaolong Cheng#, Zheng Shen, Jianyi Yang, Shih-Hsin Lu, Yongping Cui*. ECRG2 Disruption Leads to Centrosome Amplification and Spindle Checkpoint Defects Contributing Chromosome Instability. Journal of Biological Chemistry. 2008, 283(9)5888-5898.                                                IF= 5.808

   
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