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2023-09-22 19:06:54       来源:

基础医学院研究生导师个人信息

姓    名

卞伟

性   别

出 生 年

1972年

系/教研室

医用化学教研室

职    称

教授

职    务

医用化学教研室主任

导师类型

博士生导师

最高学历/学位/毕业院校

研究生/博士/山西大学

E-mail

bianwei2006@163.com

学科专业

纳米医学

研究方向

纳米材料;荧光探针;癌症诊疗一体化平台

工作单位

山西医科大学

人才称号/学术兼职

“癌症、心脑血管、呼吸和代谢性疾病防治研究”国家科技重大专项项目、山西省科技奖和山西省自然科学基金的评审专家;中华医学会医学化学分会副理事长;山西省教授协会副会长;山西省卫健委重大公共卫生项目"全国儿童口腔疾病综合干预项目"山西省技术指导组专家;山西省化学会副秘书长;山西省药学会学术部委员;全国工业过程测量控制和自动化标准化技术委员会分析仪器分技术委员会委员;山西省名优土特新产品协会团体标准管理专业委员会副主任委员。

学习工作经历

教育经历:

2010/09–2015/07 山西大学化学化工学院 分析化学 博士

1996/09–1999/07 山西大学分子科学研究所 生物无机化学 硕士1992/09–1996/07   山西大学化学化工学院 化学 学士

科研与学术工作经历:

2015/12–至今 山西医科大学基础医学院化学教研室 教授

2014/05–2015/05   香港浸会大学环境与国家重点实验室 访学

2006/10–2015/11   山西医科大学基础医学院化学教研室 副教授

2008/09–2009/07   山西大学分子科学研究所 全国青年骨干教师高级访问学者

1999/07–2006/10   山西医科大学基础医学院化学教研室 讲师

主持的科研

/教学项目

1.        中央引导地方科技发展资金,YDZJSX2024C028,面向 Her-2 阳性乳腺癌智能纳米诊疗探针的构建及其转化研究,2024.7-2026.6,120万元,在研,主持

2.        “双一流”创建科技专项-基础临床合作,BYJL025,双金属异质结可控构建及其在肿瘤光催化/免疫治疗中的研究,2024.1-2026.12,20万元,在研,主持

3.        2023年度忻州市重点研发计划(社会发展领域)项目,20230303,金属有机框架纳米复合物在非小细胞肺癌的化疗/化学动力/蛋白质协同诊疗作用的研究,2023.12-2025.12,3万元,在研,主持

4.        山西省自然科学基金,面上项目,202203021221186,近红外光激活多功能纳米复合物用于肿瘤多模成像和多效协同诊疗的研究,2023.1-2025.12,9万元,在研,主持

5.        2021吕梁市引进高层次科技人才重点研发计划(社会发展),2021RC-2-33,多功能靶向纳米复合材料的构建及在肿瘤治疗中的应用,2021.11-2023.11,25万元,在研,主持

6.        横向项目,2F022022006,银杏中总黄酮和总内酯的共富集和纯化工艺研究,2022.03-2024.03,10万元,在研,主持

7.        2021晋中市科技重点研发计划(社会发展),Y213003,多功能靶向纳米复合材料的构建及在肿瘤治疗中的应用,2021.06-2023.06,10万元,在研,主持

8.        2021年卓越医生教育培养计划2.0指令性教改项目,XJZL20210304,围绕纳米科学与技术创建诊疗一体化系列课程——搭建转换桥梁,2021.06-2023.05,0.5万元,在研,主持

代表性成果

(论文/专利/专著等)

(1)       Zhijie Jing, Xiaorui Zhang, Yimin Jin, Jianhua   Wang, Chaofan Chai and Wei Bian*. Nanocomposites Based on Layered   Double Hydroxides Loaded with Curcumin and Carbon Nitride Quantum Dots for   Combined Chemotherapy and Chemodynamic Therapy of Tumors. Journal of   Inorganic and Organometallic Polymers and Materials. https://doi.org/10.1007/s10904-024-03549-8.  

(2)       Shaofang Ma,Yan Zhang, Zihan Zhu, Deping Wang,   Xin Zhou, Jing Wang, Wei Bian and Xinjing Tang. Nucleolus-Targeting   Carbon Dot Nanocomplexes for Combined Photodynamic/Photothermal Therapy.   Molecular Pharmaceutics 2024. DOI: 10.1021/acs.molpharmaceut.4c01211.   Molecular Pharmaceutics.

(3)       Bo Li, Jieyin Wei, Ying Jin and Wei Bian*.   An off-on fluorescent probe based on N,S-GQDs/CoOOH nanocomplexes for in   vivo analysis of ascorbic acid. New Journal of Chemistry. 2025, 49,   943 - 950.

(4)       Jianhua Wang , Wenjie Liu, Jing Li, Yalin Cui,   Yichen Gong , Yumin Feng , Hongyan Jia , Wei Bian. A promising   platform for the rapid and sensitive sensing of mercury ion and its   applications in biological and environmental system. Journal of Molecular   Structure. 1322 (2025) 140446.

(5)       Yuheng Pei, Miao Liu, Cui He, Hongfang Chen,   Jing Li, Li Zhang, Mengting Zhang, Martin M.F. Choi, Hongyan Jia*, Wei   Bian*. Application of pH and hyaluronidase dual-responsive   mesoporous carbon nitride nano-drug delivery system for chemodynamic therapy   and chemotherapy combination therapy of non-small cell lung cancer. Applied   Materials Today. 41 (2024) 102469.

(6)       Peigang Zhang , Lingling Zheng , Xiaorui Zhang   , Miao Liu , Mingli Li , Mengting Zhang , Jian-Lin Wu , Martin Choi , Wei   Bian*. Mesoporous Graphene Oxide Nanocomposite Effective for   Combined Chemo/Photo Therapy Against Non-Small Cell Lung Cancer[J].   International Journal of Nanomedicine, 2024: 7493-7508.

(7)       Wei Bian,   Xi Hu, Ruixue Xiao, Rui Yao, Bo Zhang, Mingjian Zhu, Tiangi Liu, Yamin Liu,   JingLi, Peihua Lin, An Xie, Fangyuan Li, and Daishun Ling. Catalytic   Dual-Mode Immunotherapy: Anisotropic AuPt Heterostructure Decorated with   Starry Pt Nanoclusters for Robust Cancer Photometalloimmunotherapy. Advanced   Science. 2024, 2403116.

(8)       Mingyu Gan, Yingqi Wang, Fei Wang, Jie Tan,   Yuheng Pei, Jianhua Wang, Martin M.F.Choi, Wei Bian*.   Fluorescent sensing platform based on polyethyleneimine-protected copper   nanoclusters for detection of chromium (VI) in real samples.    Luminescence. 2024, 39(2), e4689.

(9)       Wenjing He,   Ying   Jin,   Baoping Wang,   Jie   Tan,   Wenjia Yan,   Hong   Xiao,   Martin M. F. Choi, Wei Bian*.   Multifunctional nanocomposites based on graphite-phase carbon nitride quantum   dots-silver nanospheres for combined photothermal-photodynamic anti-tumor   therapy. New Journal of Chemistry, 2024,48, 3957-3965.

(10) Mingyu Gan, Rui Yao, Baoping Wang, Jiarong Li, Ning Wang, Martin   M. F. Choi, Wei Bian*. 3-Aminophenylboronic Acid   Modified Carbon Nitride Quantum Dots as Fluorescent Probe for Selective   Detection of Dopamine and Cell Imaging. Methods and   Applications in Fluorescence. 2024,12(2),025001.

(11) Zihan Zhu,Peigang Zhang,Kexin An,Kaihua Zhao,Xianghui Chen,Yuheng Pei,Martin M. F. Choi,Ning Wang*,Wei Bian*. pH/Hyaluronidase dual responsive nano drug delivery systems for   photothermal/chemotherapy combined treatment for non-small cell lung cancer. New Journal of Chemistry. 2023,47, 21175-21182.

(12) Feiyan Yu, He Wang, Qianqian Wang, Baoling Zhao, Zhenni Zhao*, Wei   Bian*. Evaluation of bi-directional causal association between   periodontal disease and erectile dysfunction: a two-sample Mendelian   randomization study. Clinical Oral Investigations.  27, 5895–5903   (2023).

(13) Shaofang Ma, Zihan Zhu, Jianfei Xu, Jing Wang, Xinjing Tang*,   Wei Bian**. One-step synthesis of novel carbon dots through cross   amide formation of benzene-1,3,5-triamine and trimethyl   1,3,5-benzenetricarboxylate for fluorescence Hg2+ detection. Dyes and Pigments. 2023, 218, 111485.

(14) Juan Ren, Jianping Rao, He Wang, Wenjing He, Jinnan Feng, Danni   Wei, Bin Zhao, Xing Wang, Wei Bian*. Synergistic   remineralization of enamel white spot lesions using mesoporous bioactive   glasses loaded with amorphous calcium phosphate. Frontiers   in Bioengineering and Biotechnology. 2023, 11, 1109195.

(15) Shuyun Guo, Lingling Zheng, Wenjing He,   Chaofan Chai, Xianghui Chen, Shaofang Ma, Ning Wang, Martin M.F. Choi, Wei   Bian*. S,O-doped carbon nitride as a fluorescence probe for the   label-free detection of folic acid and targeted cancer cell imaging. Arabian   Journal of Chemistry. 2023,16(3):104520.

(16) Xiaohua Yang, Peigang Zhang, Jie Tan, Xuebing Li, Weidong Zhang, Wei   Bian*, Martin, M.F. Choi. B-GQDs@GSH as a highly selective and   sensitive fluorescent probe for the detection of Fe3+ in water   samples and intracellular. Journal   of Analysis and Testing. 2023, 7, 147–156.

(17) Xiaohua Yang, Wenjing He, Mingyu Gan, Shaomin Shuang, Martin M.F.   Choi, Wei Bian*. Dual-response ratiometric   fluorescent probe for visual and colorimetric detection of tetracycline.   Journal of Materials Science, 2023, 58: 3920–3933.

获奖及个人荣誉

(1)    山西省科学技术奖,2023年2月,省级

(2)    2023年全省“五小”创新大赛优秀成果,2023年9月,省级

(3)    优秀教师,2023年9月,校级

(4)    优秀人才工作者,2024年2月,校级

研究生培养

已毕业研究生:23名;在读研究生:15名。