生物化学与分子生物学您现在的位置是: 学院首页 >> 人才建设 >>

帅旗志
2025-03-26 09:29:52       来源:

基础医学院研究生导师个人信息

   

帅旗志

 

1989

/教研室

生化教研室

   

副教授

   

导师类型

硕士生导师

最高学历/学位/毕业院校

   研究生/博士/南开大学

E-mail

shuaiqizhi@sxmu.edu.cn

学科专业

生物化学与分子生物学

研究方向

再生医学、肿瘤组织工程

工作单位

出生缺陷与细胞再生山西省重点实验室

人才称号/学术兼职

担任Regenerative BiomaterialsINTEGRATIVE CANCER THERAPIES等杂志审稿人

学习工作经历

2025.1-至今   山西医科大学,基础医学院,副教授

2020.6-2024.12山西医科大学,基础医学院,讲师

2016.9-2020.3 南开大学 生物化学与分子生物学   博士

2013.9-2016.6 南开大学 生物化学与分子生物学   硕士

2009.9-2013.6 烟台大学 生物技术 本科

主持的科研

/教学项目

1.国家自然科学基金青年科学基金项目,82203221,肿瘤微环境中细胞外基质蛋白在血管生成拟态形成的机制及应用研究,2023.01-2025.1230万,主持

2.国家重点研发计划, 2020YFA0113500, 干细胞源性OTS型自然杀伤细胞高效获取体系建立及其异体移植的肿瘤免疫治疗策略研究, 2020.10-2024.12, 567, 任务负责人(184万)

3.山西省应用基础研究计划青年项目,202103021223227,肿瘤微环境中基质蛋白在血管生成拟态调控机制及体外肿瘤模型中的应用研究,2022.01-2024.124万,主持

4. 山西省高等教育“百亿工程”科技引导专项,BYJL036HGF协同槲皮素功能化微球介导间充质干细胞聚集体对肝纤维化的作用及机制研究,2024.01-2025.1220万,主持

5. 山西医科大学校级博士启动基金项目,XD2015,肿瘤微环境体外构建血管生成拟态模型及应用研究,2021.01-2025.1220万,主持

代表性成果

(论文/专利/专著等)

1. Q. Shuai, Y. Liang, X. Xu, Z.   Halbiyat, X. Wang, J. Cheng, J. Liu, T. Huang, Z. Peng, L. Wang, S. He, H.   Zhao, Z. Liu, J. Xu, J. Xie. Sodium alginate hydrogel integrated with type   III collagen and mesenchymal stem cell to promote endometrium regeneration   and fertility restoration. International Journal of Biological   Macromolecules, 2023, 253: 127314. (第一作者,1区,IF=8.2)

2. Q. Shuai, X. Xu, Y. Liang, Z.   Halbiyat, X. Lu, Z. Hu, Z. Peng, J. An, Z. Feng, T. Huang, H. Zhao, Z. Liu, J.   Xu, J. Xie. Engineered in vivo and in vitro tumor model recapitulates   vasculogenic mimicry signatures in melanoma. Bioengineering &   Translational Medicine, 2024, e10648. (第一作者,2区,IF=7.4)

3. Q. Shuai, L. Cao, Z. Qin, Y.   Zhang, Z. Gu, J. Yang. VE-cadherin fusion protein substrate enhanced the   vasculogenic mimicry capability of hepatocellular carcinoma cells. Journal of   Materials Chemistry B, 2020, 8(8): 1699-1712. (第一作者,3区,IF=7)

4. M. Ge, L. Sun, D. Wang, C. Hei, T.   Huang, Z. Xu, Q. Shuai. Enhancement of therapeutic potential of   mesenchymal stem cell by IGF-1 delivery in PLGA microspheres for tissue   regeneration. Regenerative Therapy, 2024, 27: 112-119. (通讯作者,3区,IF=4.3)

5. J. Ren, Z. Li, X. Shi, T. Lv, X. Li,   M. Ge, Q. Shuai, T. Huang. Exploring the efficacy of BMSC   transplantation via various pathways for treating cholestatic liver fibrosis   in mice. Biomed Environ Sci, 2024, 37(x): 1-12. (通讯作者,3区,IF=3)

6. T. Huang, Z. Shang, L. Nie, H. Diao, Q.   Shuai, J. Ren, J. Xu, J. Xie. m6A modified ATG9A is required in   regulating autophagy to promote HSCs activation and liver fibrosis. Cellular   Signalling, 2025, 127:111619. (通讯作者,2区,IF=4.4)

7. Y. Liang, Q. Shuai, X. Zhang, S.   Jin, Y. Guo, Z. Yu, X. Xu, R. Ao, Z. Peng, H. Lv, S. He, C. Wang, G. Song, Z.   Liu, H. Zhao, Q. Feng, R. Du, B. Zheng, Z. Chen, J. Xie. Incorporation of   Decidual Stromal Cells Derived Exosomes in Sodium Alginate Hydrogel as an   Innovative Therapeutic Strategy for Advancing Endometrial Regeneration and   Reinstating Fertility. Advanced Healthcare Materials, 2024, 2303674. (共同一作,2区,IF=10)

8. Y. Liang, Q. Shuai, Y. Wang, S.   Jin, Z. Feng, B. Chen, T. Liang, Z. Liu, H. Zhao, Z. Chen, C. Wang, J. Xie.   1-Nitropyrene exposure impairs embryo implantation through disrupting   endometrial receptivity genes expression and producing excessive ROS.   Ecotoxicology and Environmental Safety, 2021, 227: 112939. (共同一作,2区,IF=6.8)

9. K. Xu, Q. Shuai, X. Li, Y.   Zhang, C. Gao, L. Cao, F. Hu, T. Akaike, J. Wang, Z. Gu, J. Yang. Human   VE-cadherin fusion protein as an artificial extracellular matrix enhancing   the proliferation and differentiation functions of endothelial cell.   Biomacromolecules 2016, 17, 3, 756766. (2区,IF=5.5)

10. G. Du, J. Zhang, Q. Shuai, L.   Li, Q. Zhang, R. Shi. Development of alginate-collagen interpenetrating   network for osteoarthritic cartilage by in situ softening. International   Journal of Biological Macromolecules, 2024, 131259. (1区,IF=8.2)

11. L. Cao, Y. Zhang, M. Qian, X. Wang, Q.   Shuai, C. Gao, R. Lang, J. Yang. Construction of multicellular aggregate   by E-cadherin coated microparticles enhancing the hepatic specific   differentiation of mesenchymal stem cells. Acta Biomaterialia, 2019, 95:   382-394. (1区,IF=9.7)

12. Y. Zhang, K. Xu, D. Zhi, M. Qian, K.   Liu, Q. Shuai, Z. Qin, J. Xie, K. Wang, J. Yang. Improving vascular   regeneration performance of electrospun poly (ε-caprolactone) vascular grafts   via synergistic functionalization with VE-cadherin/VEGF. Advanced Fiber Materials,   2022, 4(6): 1685-1702. (1区,IF=16.1)

13. Z. Feng, B. Zhou, Q. Shuai, Y.   Wei, N. Jin, X. Wang, H. Zhao, Z. Liu, J. Xu, J. Mu, J. Xie. Development of   an alcoholic liver disease model for drug evaluation from human induced   pluripotent stem cell-derived liver organoids: ALD model from hiPSC-derived   liver organoids. Acta Biochimica et Biophysica Sinica, 2024, 56(10): 1–13. (2区,IF=3.3)

14. T. Huang, C. Zhang, Z. Shang, Q.   Shuai, L. Nie, J. Ren, S. Hou, J. Xie. Bone mesenchymal stem cells   improve cholestatic liver fibrosis by targeting ULK1 to regulate autophagy   through PI3K/AKT/mTOR pathway. Stem Cells Translational Medicine, 2024, 13(7):   648-660. (2区,IF=5.4)

15. Y. Zhang, H. Mao, C. Gao, S. Li, Q.   Shuai, J. Xu, K. Xu, L. Cao, R. Lang, Z. Gu, J. Yang. Enhanced Biological   Functions of Human Mesenchymal Stem‐Cell Aggregates Incorporating E‐Cadherin‐Modified   PLGA Microparticles. Advanced Healthcare Materials, 2016, 5 (15): 1949-1959. (2区,IF=10)

16. 杨军; 帅旗志; 张妍 ;   钙粘素融合蛋白体外诱导肿瘤血管拟态形成的应用, 2022-9-16, 中国, ZL202011611161.6

17. 解军; 徐馨蕊;   帅旗志; 梁宇翔; 陆昕; 刘志贞; 赵虹; 王磊 ; 一种实验鼠背部皮下注射固定装置, 2022-7-15, 中国, ZL202123015069.6

获奖及个人荣誉

1. 2024年获干细胞与组织工程国际高峰学术会议暨国际心血管科学院首届亚洲分会会议 青年学术报告一等奖

2. 入选山西省2024年度研究生教育创新计划“优秀研究生导师团队”

研究生培养

指导硕士研究生8名。