代表性成果 （论文/专利/专著等） |
(1) Cui Y, Chen H, Xi R, Cui H, Zhao Y, Xu E, Yan T, Lu X, Huang F, Kong P, Li Y, Zhu X, Wang J, Zhu W, Wang J, Ma Y, Zhou Y, Guo S, Zhang L, Liu Y, Wang B, Xi Y, Sun R, Yu X, Zhai Y, Wang F, Yang J, Yang B, Cheng C, Liu J, Song B, Li H, Wang Y, Zhang Y, Cheng X, Zhan Q, Li Y, Liu Z. Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma. Cell Res. 2020 May 12. doi: 10.1038/s41422-020-0333-6. (IF= 20.507) (2) Pengzhou Kong(#), Enwei Xu(#), Yanghui Bi(#), Xiaoqin Xu(#), Xue Liu(#), Bin Song, Ling Zhang, Caixia Cheng, Ting Yan, Yu Qian, Jian Yang, Yanchun Ma, Heyang Cui, Yuanfang Zhai, Binbin Zou, Xiangchen Liu, Yikun Cheng, Shiping Guo, Xiaolong Cheng, Yongping Cui(*). Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC. Theranostics, 2020, 10(4): 1798-1813. doi:10.7150/ thno.38210. (第一作者，IF=8.579)； (3)Yanghui Bi(#), Shixing Guo(#), Xiaoqin Xu(#), Pengzhou Kong(#), Heyang Cui(#), Ting Yan, Yanchun Ma, Yikun Cheng, Yunqing Cheng, Xue Liu, Ling Zhang, Caixia Cheng, Enwei Xu, Yu Qian, Jian Yang, Bin Song, Hongyi Li, Fang Wang, Xiaoling Hu, Xiangchen Liu, Xia Niu, Yuanfang Zhai, Jing Liu, Yaoping Li, Xiaolong Cheng, Yongping Cui(*). Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma. Cell Death & Disease, 2020 11(4):296. doi: 10.1038/s41419-020-2492-2.（并列第一作者，IF=6.304）； (4)Bi Y(#), Kong P(#), Zhang L(#), Cui H(#), Xu X(#), Chang F(#), Yan T, Li J, Cheng C, Song B, Niu X, Liu X, Liu X, Xu E, Hu X, Qian Y, Wang F, Li H, Ma Y, Yang J, Liu Y, Zhai Y, Wang Y, Zhang Y, Liu H, Liu J, Wang J(*), Cui Y, Cheng X(*). EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma. J Cancer, 2019, 10(22):5413-5426. doi: 10.7150/jca.34261.（并列第一作者，IF=3.182）； (5)Yan T(#), Cui H(#), Zhou Y(#), Yang B(#), Kong P(#), Zhang Y(#), Liu Y, Wang B, Cheng Y, Li J, Guo S, Xu E, Liu H, Cheng C, Zhang L, Chen L, Zhuang X, Qian Y, Yang J, Ma Y, Li H, Wang F, Liu J, Liu X, Su D, Wang Y, Sun R, Guo S, Li Y, Cheng X, Liu Z, Zhan Q(*), Cui Y(*).Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma. Nat Commun, 2019, 11;10(1):1670. doi: 10.1038/s41467-019-09255-1. （并列第一作者，IF=12.121）； (6)Kong PZ(#*), Li GM, Tian Y, Song B, Shi R. Decreased expression of FOXF2 as new predictor of poor prognosis in stage I non-small cell lung cancer. Oncotarget, 2016, 7(34):55601-55610 doi: 10.18632/oncotarget.10876. (第一作者，通信作者，IF=5.168) (7)Hu X(#), Zhai Y(#), Kong P(#), Cui H(#), Yan T, Yang J, Qian Y, Ma Y, Wang F, Li H, Cheng C, Zhang L, Jia Z, Li Y, Yang B, Xu E, Wang J, Yang J, Bi Y, Chang L, Wang Y,Zhang Y, Song B, Li G, Shi R, Liu J, Zhang M, Cheng X, Cui Y(*). FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer. Cancer Letters, 2017, 397:83-93. doi: 10.1016/ j.canlet.2017.03.033. (并列第一作者, IF=6.375) (8)Song B(#), Cui H(#), Li Y(#), Cheng C(#), Yang B(#), Wang F(#), Kong P(#), ……, Zhan Q(*), Cui Y(*). Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China. Oncotarget. 2016 ,19;7(3):3599-613.（并列第一作者，IF=6.359） (9)Wang QS(#), Kong PZ(#), Li XQ, Yang F, Feng YM(*). FOXF2 deficiency promotes epithelial-mesenchymal transition and metastasis of basal-like breast cancer. Breast Cancer Research. 2015, 17(30): doi:10.1186/s13058-015-0531.（并列第一作者，IF=5.88.） (10)Ling Zhang(#), Yong Zhou(#), Caixia Cheng(#), Heyang Cui(#), Le Cheng(#), Pengzhou Kong(#), Jiaqian Wang(#), Yin Li(#),……Qimin Zhan(*), Yongping Cui(*). Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. Am J Hum Genet.2015, 2;96(4):597-611.（并列第一作者，IF=10. 987） |
