代表性成果 （论文/专利/专著等） |
代表性论文 1. Feng X, Chen J, Lian J, Dong T, Gao Y, Zhang X, Zhai Y, Zou B, Guo Y, Xu E, Cui Y*, Zhang L*. The glycogene alterations and potential effects in esophageal squamous cell carcinoma. Cell Mol Life Sci. 2024, 81(1):481. 2. 2. Guo Y, Wang X, Du Y, Zhao Y, Gao L, Hao Y, Lv D, Feng X, Zhai Y, Zou B, Han J, Xu E, Yang Y, Yang B, Xi Y*, Zhang L*. The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A11. Cancer Gene Ther. 2024,31(10):1498-1510. 3. Yang X, Jiao Y, Zhang Y, Sun M, Gao Y, Zhou Y, Xiao H, Ren J, Zhou Z, Zhai Y, Song B, Zhang L*, Kong P*. Oseltamivir enhances 5-FU sensitivity in esophageal squamous carcinoma with high SPNS1. Biomed Pharmacother. 2024 ,173:116367. 4. Feng X, Gao L, Shen X, Li M, Wang X, Hao Y, Chen J, Zhai Y, Zou B, Yao S, Guo Y*, Zhang L*. A pan-cancer analysis of prognostic significance and immunological role of lysosomal-associated membrane protein 3. J Cell Mol Med. 2024, 28(3): e18088. 5. Ren J, Kong P, Wang Y, Guo D, Zhang L*. Copy number variations in esophageal squamous cell carcinoma: Emerging cancer drivers and biomarkers. Oncol Rep. 2024, 51(1): 8. 6. Guo Y, Hao Y, Shen L, Du Y, Wang X, Gao L, Feng X, Zhai Y, Liu Z, Xu E, Yang Y, Xi Y, Yang B*, Zhang L*. TSTA3 overexpression promotes malignant characteristics in LUSC by regulating LAMP2-mediated autophagy and tumor microenvironment. Cancer Cell Int. 2023, 23(1):285. 7. Gao Y, Shen L, Dong T, Yang X, Cui H, Guo Y, Ma Y, Kong P, Cheng X, Zhang L*, Cui Y*. An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma. J Transl Med. 2022, 20(1):285. 8. Zhang L, Zhang J, Li S, Zhang Y, Liu Y, Dong J, Zhao W, Yu B, Wang H, Liu J. Genomic amplification of long noncoding RNA HOTAIRM1 drives anaplastic thyroid cancer progression via repressing miR-144 biogenesis. RNA Biol. 2021, 18(4):547-562. 9. Zhang L, Gao Y, Zhang X, Guo M, Yang J, Cui H, Kong P, Niu X, Bi Y, Xu J, Yan T, Ma Y, Yang J, Qian Y, Wang F, Li H, Liu F, Cheng X, Cui Y. TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2. Theranostics. 2020, 10(24):11339-11358. 10. Zhang L, Niu X, Bi Y, Cui H, Li H, Cheng X. Potential Role of Targeting KDR and Proteasome Inhibitors in the Therapy of Esophageal Squamous Cell Carcinoma. Technol Cancer Res Treat. 2020, 19:1533033820948060. 11. Zhang L, Zhang X, Zhang H, Liu F, Bi Y, Zhang Y, Cheng C, Liu J. Knockdown of SF3B1 Inhibits Cell Proliferation, Invasion and Migration Triggering Apoptosis in Breast Cancer via Aberrant Splicing. Breast Cancer. 2020, 27(3):464-476. 12. Zhang L, Zhou Y, Cheng C, Cui H, Cheng L, Li Y, Chen W, Song B, Wang F, Zhan Q*, Cui Y*. Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. Am J Hum Genet, 2015, 96(4):597-611. 13. Zhang L, Shi R, He C, Cheng C, Song B, Cui H, Zhang Y, Zhao Z, Bi Y, Yang X,Miao X, Guo J, Chen X, Wang J, Li Y, Cheng X, Liu J, Cui Y*. Oncogenic B-Raf(V600E) abrogates the AKT/B-Raf/Mps1 interaction in melanoma cells. Cancer Lett, 2013, 337(1):125-132. 专利 1. TSTA3与LAMP2作为靶标物在食管鳞癌细胞转移检测、药物筛选中的应用，ZL 2020 1 0797744.6，第一发明人 2. 一种消毒棉签，ZL 2019 2 1930098.5号，第一发明人 3. 一种注射器用遮光套，ZL 2019 2 1577077.X号，第一发明人 4. 细胞密度控制仪及其方法、应用，ZL 2018 1 0424968.5，第十发明人 5. POFUT1 作为食管鳞癌诊断标志物、药物筛选及预后评价试剂中的应用，2023110282554，第一发明人 |
