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赵慧芳
2025-03-25 10:38:56       来源:

医学技术专业学位硕士研究生导师个人信息

   

赵慧芳

 

198811

/教研室

医学技术

   

副教授

   


导师类型

硕导

最高学历/学位/毕业院校

中国科学院大学

E-mail

zhaohf1108@163.com

学科专业

分子医学

研究方向

分子影像和质谱成像技术在慢性重大疾病精准诊断研究

工作单位

山西医科大学基础医学院

人才称号/学术兼职

山西省抗癌协会肿瘤样本整合研究常务委员

学习工作经历

12019-07 今,山西医科大学,基础医学院

22016-092019-06,中国科学院大学,物理化学,博士

32012-092015-06,南昌大学,分析化学,硕士

42008-092012-07,太原师范学院,化学,学士

主持的科研

/教学项目

1.国家卫生健康委医药卫生科技发展研究中心,国家科技重大专项子课题,2024ZD0531102,早期心肾代谢综合征的多维影像基因代谢组图谱建立,2025-022029-01400万,在研,主持

2. 国家自然科学基金委员会,青年科学基金项目,22004082,可控MALDI碳基质的构建及其在肝细胞癌小分子标志物精准筛选中的应用,2021-01-012023-12-3124万,结题,主持;

3.中国博士后科学基金会,中国博士后科学基金面上项目,2023M742173,磁共振定量成像联合MALDI MSI技术精准诊断急性肾损伤研究,2024-012025-128万,在研,主持;

4. 山西省教育厅,高校科技创新计划项目,2020L0173,基质辅助激光质谱传感的唾液分析用于胃癌的早期诊断研究,2020-072022-063万,在研,主持。

代表性成果

(论文/专利/专著等)

代表性论文:

1. Huifang Zhao*, Siyi Jiang, Shuyu Zhai, Xiaoyang Lv,   Chaoqun Shi, Yi Chen, Ruiping Zhang*. Recent advances of intelligent polymer   gels as active carriers for medical imaging-guided cancer therapy: A review. International   Journal of Biological Macromolecules 2025, 301, 140451 (SCI一区,IF=7.7)

2. Yuan Chen, Jiaying Che, Jiagui Wang, Yuanyuan Tuo, Huayu Zhao,   Yi Chen, Luheng Sai, Huifang Zhao*, and Ruiping Zhang*. Functional   Melanin Nanoparticles-Assisted Laser Desorption Ionization Mass Spectrometry   for High-Sensitivity Detection of TBBPA and TBBPS Contaminations in   Animal-Derived Foodstuffs. Journal of Agricultural and Food Chemistry 2024,   72, 12, 6744–6753  (SCI 一区, IF=6.1)

3. Siwen Yi, Huayu Zhao, Xiunan Xu, Bowei   Guan, Huifang Zhao*, Ruiping Zhang*. A photoresponsive multifunctional   carbon-based nanozymes for synergistic detecting and depleting GSH in cancer   therapy. Applied Surface Science 2024, 655, 159568.  (SCI 二区,IF=6.7)

4. Huifang Zhao, Huayu Zhao, Jie   Wang, Jianying Ren, Jia Yao, YanqiuLi,* and RuipingZhang*. Bovine   Omasum-Inspired Interfacial Carbon-Based Nanocomposite for Saliva Metabolic   Screening of Gastric Cancer. Analytical Chemistry 2023, 95, 11296.                (SCI一区,IF=8.008)

5. Huifang Zhao, Xiaoxiang Zhang, Junying Wang,* Junzhong   Wang.* N, S co-doped porous carbon nanosheet foam as MALDI matrix for   efficient and direct profiling of biomolecules and environmental contaminants.   Applied Surface Science 2023, 623, 157052        (SCI一区,IF=7.392)

6. Huifang Zhao, Yanqiu Li,   Huayu Zhao, Zheng Zhao, Junying Wang,* Ruiping Zhang*. Yolk-shell Ni/NiO   anchored on N-doped graphene synthesized as dual-ion MALDI matrix for   detecting and imaging bioactive small molecules. Journal of Colloid and   Interface Science 2022, 613, 285    (SCI一区,IF=9.965)

7. Huifang Zhao, Yanqiu Li, Jie   Wang, Miao Cheng, Zheng Zhao, Huinian Zhang, Congwei Wang, Junying Wang, Yan   Qiao,* Junzhong Wang.* Dual-ion-mode MALDI MS detection of small molecules   with the O–P,N-doped carbon/graphene matrix. ACS Applied Materials &   Interfaces 2018, 10, 37732  (SCI二区, IF: 10.383)

8. Huifang Zhao, Ruping Liang,   Jingwu Wang and Jianding Qiu.* One-pot synthesis of GO/AgNPs/luminol   composites with electrochemiluminescence activity for sensitive detection of   DNA methyltransferase activity. Biosensors and Bioelectronics 2015, 63,   458–464.                    (SCI一区,IF: 12.545)

9. Huifang Zhao, Huayu Zhao, Jie Wang, Yulong Liu, Yanqiu   Li,* Ruiping Zhang.* The local electric field effect of onion-like carbon   nanoparticles for improved laser desorption/ionization efficiency of   saccharides. Colloids and Surfaces B: Biointerfaces 2022, 211, 112321                        (SCI二区,IF=5.999)

10. Huifang Zhao, Jie Wang, Huayu Zhao, Yulong Liu, Yanqiu   Li,* Ruiping Zhang.* One-step synthesis of N, B-codoped carbon nanofiber as a   novel matrix for high-throughput and efficient laser desorption/ionization   mass spectrometry analysis. Microchemical Journal 2021, 164,   105966       (SCI二区,IF=5.304)

11. Huifang Zhao, Ruping Liang, Jingwu Wang, Jian-Ding   Qiu.* A dual-potential electrochemiluminescence ratiometric approach based on   graphene quantum dots and luminal for highly sensitive detection of protein   kinase activity. Chemical Communications 2015, 51, 12669-12673.          (SCI二区,IF:   6.065)

专利:

1. 张瑞平;赵慧芳;赵华宇;刘玉龙;镍颗粒修饰碳基质、制备和代谢小分子的质谱分析应用,2022-11-01,中国,ZL202110280944.9 (专利)

2. 王俊中;赵慧芳;一种石墨烯单原子金复合材料及其制备方法和应用,2020-01-17,中国,ZL201810836712.5 (专利)

3. 王俊中;赵慧芳;一种双杂原子掺杂的石墨烯/多孔碳复合物的制备和质谱分析应用,2021-04-02,中国,ZL201811154694.9 (专利)

 

获奖及个人荣誉

研究生培养

已毕业硕士研究生1名,在读硕士生7名,协助培养4