我校在精神分裂症调控紊乱机制研究中取得系列进展

徐勇教授的系列研究获得了与精神分裂症诊断、疗效相关的外周血基因调控因子，构建了多层面精神分裂症基因调控网络，推进了对精神分裂症基因表达调控异常分子机制的理解，提供了精神分裂症发病机制研究的新思路。

延伸阅读：

1. Zhang F^(#),Xu Y^(#), Shugart YY^(#), Yue W^(#), Qi G, Yuan G, Cheng Z, Yao J, Wang J, Wang G, Cao H, Guo W, Zhou Z, Wang Z, Tian L, Jin C, Yuan J, Liu C, Zhang D^(*).Converging Evidence Implicates the Abnormal MicroRNA System in Schizophrenia.Schizophrenia Bulletin.2015,41(3):728-735. (SCI IF:2014:8.45)

2. Ren Y, Cui Y, Li X, Wang B, Na L, Shi J, Wang L, Qiu L, Zhang K, Liu G^(*),Xu Y^(*).A co-expression network analysis reveals lncRNA abnormalities in peripheral blood in early-onset schizophrenia.Progress in Neuro-Psychopharmacology & Biological Psychiatry.2015,63:1-5. (SCI IF:2014:3.689)

3. Xu Y^(#), Shugart YY^(#),Wang G, Jin C, Zhang K, Wang J, Yu H, Zhang F^(*), Yue W^(*), Zhang D. Altered expression of mRNA profiles in blood of early-onset schizophrenia.Scientific Reports. 2016, 6:16767. (SCI IF:2014: 5.578)

4. Xu Y^(#), Shugart YY^(#), Yue W^(#), Li S, Zhang K, Liu S, Cheng Z, Wang G, Zhou Z, Jin C, Yuan J, Tian L, Zhang F^(*). Exploring transcription factors-microRNAs coregulation networks in Schizophrenia.Schizophrenia Bulletin.2016. In Press. (SCI IF:2014:8.45)

5. Zhang F^(#)(*), Yao Shugart Y^(#), Yue W^(#), Cheng Z, Wang G, Zhou Z, Jin C, Yuan J, Liu S,Xu Y^(*).Increased Variability of Genomic Transcription in Schizophrenia.Scientific Reports. 2015,5:17995. (SCI IF:2014: 5.578)