欢迎进入山西医科大学公共卫生学院
仇玉兰
仇玉兰
医学博士，教授，博士生导师，博士后合作导师
E-mail:ylqiu@sxmu.edu.cn
教育经历
2003.09-2007.06，复旦大学，毒理学，博士
1993.09-1996.06，山西医科大学，毒理学，硕士
1988.09-1993.06，山西医学院，预防医学系，学士
工作经历
1996.7-至今 山西医科大学公共卫生学院
学习经历
2014.09-2015.09，美国纽约州立大学水牛城分校访学
2009.12-2012.06，山西医科大学，公共卫生与预防医学博士后流动站
学术任职
山西省环境诱变剂学会副理事长；中国环境诱变剂学会理事；山西省毒理学会理事；中华预防医学会伤害预防与控制分会委员；中国环境诱变剂学会致癌专业委员会委员；中国环境诱变剂学会致畸专业委员会委员；中国生物物理学会自由基生物学与自由基医学分会理事；山西省优生科学协会环境与社会优生专业委员会常务委员。
荣誉获奖
获山西省高校科技进步二等奖1项(第一名)，上海市预防医学会科学技术奖三等奖(第二名)。2020年获“山西省高校师德楷模”称号，2025年获山西医科大学“三育人”先进个人。
教学情况
主要承担本科生和研究生《毒理学基础》、《毒理学进展》、《细胞和动物实验设计》等课程，参编规划教材和其他教材10余部，主持和参与校教改课题5项。
研究领域
环境污染物砷、氟以及微塑料的神经毒性；氯乙烯的遗传和表观遗传致癌机制研究
主持科研项目
1.山西省留学人员科技活动择优资助项目：老化PET微塑料经肠-脑轴致SD大鼠认知障碍的菌群代谢机制（20250022）。2025.06月-2027.06。在研，主持；
2.山西省高等学校本科教学改革创新项目。《毒理学基础》课程知识图谱构建与智慧化教学模式初探(J20250083)2025.06-2027.06。在研，主持；
3.山西省自然科学基金：肠道菌群相关色氨酸代谢在慢性低剂量砷染毒致大鼠AD样改变中的作用(202203021211246)，2023.01月-2025.12。结题，主持；
4.国家自然科学基金：DNA甲基转移酶过表达、DNA甲基化在氯乙烯致遗传物质损伤中的调控机制（81773405），2018.01.-2021.12.。结题，主持；
5.山西省回国留学人员科研资助项目： 内质网应激在氯乙烯致化学性肝脂肪变性中的作用（2016-056），2016.06 -2019.06。结题，主持；
6.山西省自然科学基金：microRNA在氯乙烯致DNA损伤和细胞周期改变中的作用（2013011059-1），2013.01.-2015.12.。结题，主持；
7.中国博士后科学基金：氯乙烯对P53介导的G1/S关卡的影响及相关基因的表达（20100471583），2010.06.-2012.06.。结题，主持；
8.山西省高等学校科技项目：纳米碳酸钙和常规碳酸钙对大鼠肺毒性的对比研究(200811013)，2008.05.-2010.05。结题，主持。
代表性论著
1.Chao Feng , Qian Zhang, Longmei Wang , Shuyuan Li , Kanglin Wang , Yifan Xu, Kun Chen , Jing Wang , Shujie Feng , Yi Lyu , Fengjie Tian , Cailing Wei, Ben Li ,Yulan Qiu*,Take-out containers as nano- and microplastics reservoirs: Diet-driven gut dysbiosis in university students . Environmental Pollution, 384 (2025) 126985.
2.Xiaoli Zhang, Jing Wang , Shuyuan Li , Kun Chen, Longmei Wang , Chao Feng, Yi Gao, Xiaoyan Yan , Qian Zhao , Ben , Jinping Zheng,*,Yulan Qiu *. Mechanism of arsenic regulation of mitochondrial damage and autophagy induced synaptic damage through SIRT1 and protective effect of melatonin in HT22 cell. Chemico-Biological Interactions 412 (2025) 111461.
3.Shuyuan Li, Jia Li, Kun Chen, Jing Wang,Longmei Wang,Chao Feng, Kanglin Wang, Yifan Xu, Yi Gao, Xiaoyan Yan,Qian Zhao,Ben Li,Yulan Qiu *.Chronic Arsenic Exposure Causes Alzheimer's Disease Characteristic Effects and the Intervention of Fecal Microbiota Transplantation in Rats, Journal of Applied Toxicology, 2025, 45(8): 1476-1486.
4.Kun Chen#,Qiuyi Zhao#,Shuyuan Li,Jing Wang,Chao Feng,Longmei Wang.Xiaoyan Yan,Ben Li, Qian Zhao,Yulan Qiu*.The Relationship Between Gut Microbiota Related Hippocampal Tryptophan Metabolite and Alzheimer’s Disease Like Neurobehavioral Changes Induced by Chronic Inorganic Arsenic Exposure in Rats. Biological Trace Element Researchhttps://doi.org/10.1007/s12011-025-04783-y, 2025.08.
5.Ben Li*, Ting Liu 1,, Yongmei Shen, Jiangnan Qin ,Xiaohan Chang,Meiqiong Wu,Jianquan Guo , Liangpo Liu , Cailing Wei , Yi Lyu, Fengjie Tian , Jinzhu Yin , Tong Wang , Wenping Zhang ,Yulan Qiu*.TFEB/LAMP2 contributes to PM0.2-induced autophagy-lysosome dysfunction and alpha-synuclein dysregulation in astrocytes.Journal of Environmental Sciences, 2024,145: 117-127.
6.Qian Zhao, Yan Hao, Xiaoqian Yang, Jie Mao, Fengjie Tian, Yi Gao, Xiaolin Tian, Xiaoyan Yan,Yulan Qiu*.Mitigation of maternal fecal microbiota transplantation on neurobehavioral deficits of offspring rats prenatally exposed to arsenic: Role of microbiota-gut-brain axis, Journal of Hazardous Materials, 2023, 457: 131816.
7.Zhang Xiao Li, Yu Sheng Nan, Qu Ruo Di,Zhao Qiu Yi,Pan Wei Zhe, Chen Xu Shen, Zhang Qian, Liu Yan, Li Jia, Gao Yi, Lyu Yi, Yan Xiao Ya, Li Ben, Ren Xue Feng, Qiu Yu Lan. Mechanism of Learning and Memory Impairment in Rats Exposed to Arsenic and/or Fluoride Based on Microbiome and Metabolome. Biomed Environ Sci, 2023 Mar 20;36(3):253-268.
8.Qiuyi Zhao, Weizhe Pan, Jia Li, Shengnan Yu,Yan Liu,Xiaoli Zhang, Ruodi Qu ,Qian Zhang, Ben Li Xiaoyan Yan, Xuefeng Ren,Yulan Qiu. Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats, Chemosphere, 2022, 308(Pt 2): 136341- 136341.
9.Yulan Qiu, Xushen Chen, Xiaoyan Yan, Jie Wang, Guan Yu, Wenyan Ma, Bo Xiao,Sarah Quinones, Xiaolin Tian, Xuefeng Ren*. Gut microbiota perturbations and neurodevelopmental impacts in offspring rats concurrently exposure to inorganic arsenic and fluoride. Environment International 140 (2020) 105763.
10.Yu-lan Qiu*, Zhi-bin Xu, Qian Wang, Jun-yang Hu, Lin Zhang, Shi-qi Chen, Yi Lyu, Cai-ling Wei, Xiao-yan Yan, Tong Wang. Association between methylation of DNA damage response-related genes and DNA damage in hepatocytes of rats following subchronic exposure to vinyl chloride. Chemosphere 227 (2019) 323-328.
11.Qian Wang, Lin Zhang, Shi-qi Chen, Wen-yan Ma, Yan-lin Guo, Yi Gao, Feng-jie Tian,Yu-lan Qiu*. Role of endoplasmic reticulum stress and oxidative stress in vinyl chloride induced hepatic steatosis in mice. Toxicology and Applied Pharmacology. 381(2019)114730.
12.Qiu YL, Wang W, Wang T, Sun P, Wu F, Zhu SM, Qian J, Jin L, Au W, Xia ZL*. DNA repair gene polymorphisms and micronucleus frequencies in Chinese workers exposed to vinyl chloride monomer.Int J Hyg Environ Health.214(3):225-230, 2011.
13.Yu-lan Qiu*,Pin Sun,Wei Wang, Tong Wang,Zhao-lin Xia. Messenger RNA expression and genetic polymorphisms of cell cycle control genes and chromosomal aberrations in Chinese vinyl chloride monomer -exposed workers. Journal of Occupational and Environmental Medicine. J Occup Environ Med. 53(12):1442-1446，2011.
14.Yu-lan Qiu, Wei Wang, Tong Wang, Jing Liu, Pin Sun, Ji Qian, Li Jin, and Zhao-lin Xia*. Genetic Polymorphisms, Messenger RNA Expression of p53, p21, and CCND1, and Possible Links with Chromosomal Aberrations in Chinese Vinyl Chloride–Exposed Workers. Cancer Epidemiol Biomarkers Prev. 17(10):2578-2584，2008.
