武美琼
工学博士，讲师，儿少卫生教研室
办公电话：0351-4135262
E-mail: wumeiqiong@sxmu.edu.cn
教育经历：
2013.9-2019.7，山西大学，环境科学，博士（硕博连读）
2009.9-2013.7，山西大学，环境科学，学士
工作经历
2019. 7-至今，山西医科大学公共卫生学院
学习经历
无
学术任职
无
荣誉获奖
荣获2020年全国高校（医学类）微课教学比赛二等奖
教学情况
主要承担本科生《儿童少年卫生学》、《妇幼保健学》、《预防医学》课程以及研究生《现代儿童少年卫生学》、《妇幼保健学》课程，主持校教改课题1项。
研究领域
环境暴露与子代健康效应研究。
代表性科研项目
1.煤烟型大气污染物SO2和PAHs复合暴露诱导肺纤维化及其表观遗传调控机制。山西省青年基金项目，201901D211331，2019.09-2022.09。
2.基于PPARa探讨新型增塑剂DINP诱导子代脂质代谢紊乱机制研究。山西省高等学校科技创新项目，2021L219，2021.08-2023.07。
3.基于关键组分探讨不同城市PM2.5诱导心脏功能紊乱。山西医科大学校级博士启动基金项目，XD1919，2020.01 – 2022.12。
4.细颗粒物（PM2.5）吸入暴露诱导心脏功能紊乱及其纤维化分子机制。山西医科大学省级博士基金项目，SD1919，2020.01 – 2020.12。
代表性论著
1.Meiqiong Wu, Qisong Xing, Huiling Duan, Guohua Qin*, Nan Sang. Suppression of NADPH oxidase 4 inhibits PM2.5-induced cardiac fibrosis through ROS-P38 MAPK pathway. Science of The Total Environment, 2022, 837:155558.
2.Meiqiong Wu, Gang Liang, Huiling Duan, Xiaofeng Yang, Guohua Qin*, Nan Sang*. Synergistic effects of sulfur dioxide and polycyclic aromatic hydrocarbons on pulmonary pro-fibrosis via mir-30c-1-3p/transforming growth factor β type II receptor axis. Chemosphere, 2019, 219, 268-276.
3. Qisong Xing#,Meiqiong Wu#, Zhen Xue, Nan Nan, Zhipeng Yan, Shuyue Li, Yang Yun*, Guohua Qin*, Nan Sang. Biochemical evidence of PM2.5 critical components for inducing myocardial fibrosis in vivo and in vitro. Science of The Total Environment, 2023, 857: 159258.
4. Qisong Xing#,Meiqiong Wu#, Rui Chen#, Gang Liang, Huiling Duan, Shuyue Li, Yuqian Wang, Lei Wang, Caixiu An, Guohua Qin*, Nan Sang. Comparative studies on regional variations in PM2.5 in the induction of myocardial hypertrophy in mice. Science of The Total Environment, 2021, 775: 145179.
5. Guohua Qin,Meiqiong Wu, Jiaoxia Wang, Zhifang Xu, Xia Jin, Nan Sang*. Sulfur dioxide contributes to the cardiac and mitochondrial dysfunction in rats. Toxicological Sciences, 2016, 151, 334-346.
6. Guohua Qin,Meiqiong Wu, Nan Sang*. Sulfur dioxide and benzo(a)pyrene trigger apoptotic and anti-apoptotic signals at different post-exposure times in mouse liver. Chemosphere, 2015. 139, 318-325.
7. Zhipeng Yan#, Shuyue Li#, Rui Chen#, Haohan Xie,Meiqiong Wu, Nan Nan, Qisong Xing, Yang Yun, Guohua Qin, Nan Sang. Effects of differential regional PM2.5 induced hepatic steatosis and underlying mechanism. Environmental Pollution. 2023 Apr 15; 323:121220.
8. Li B, Chang X, Liang X, Liu T, Shen Y, Zhang Q, Yang X, Lyu Y, Liu L, Guo J,Wu M, Gao Y, Yan X, Wang T, Zhang W, Qiu Y, Zheng J. The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter. Sci Total Environ. 2023, 867:161416.
9. Xiaomei Kong*, Ru Chen, Lina Zhang,Meiqiong Wu, Juan Wu, Yangyang Wei, Wenjuan Dai, Yi Jiang. ESR2 regulates PINK1-mediated mitophagy via transcriptional repression of microRNA-423 expression to promote asthma development. Pharmacol Res, 2021, 174: 105956.
10. Shufang Guo, Ru Chen, Lina Zhang,Meiqiong Wu, Yangyang Wei, Wenjuan Dai, Yi Jiang, Xiaomei Kong*. microRNA-22-3p plays a protective role in a murine asthma model through the inhibition of the NLRP3-caspase-1-IL-1β axis. Exp Physiol. 2021, 106(8): 1829-1838.
11.武美琼,王新静,刘瑾,李颖君,杨佳,路上云,王莉*.双酚A替代物对小鼠的心肌毒性研究.环境科学学报, 2023-02-21: 1-8.
12.秦国华*,武美琼,桑楠. SO2和BaP复合暴露诱导小鼠心脏线粒体损伤的分子机制初探.环境科学学报, 2015, 35(8): 2620-2625.
13.秦国华*,武美琼,桑楠. SO2和BaP复合暴露诱导小鼠肺线粒体损伤的分子机制.中国环境科学, 2015, 35(11): 3496-3501.
14.邢颀颂,梁刚,武美琼,秦国华*,桑楠.不同城市PM2.5对易感小鼠线粒体损伤的影响.中国环境科学, 2019, 39(12): 5319-5325.
15.刘瑾,张柳源,武美琼,李志红,郭彩霞,王莉*. 2018—2020年太原市大气污染物浓度对孕期睡眠质量的影响.中国预防医学杂志, 2022: 1-9[2023-03-29]
16.姬晓彤,岳慧峰,武美琼,白剑英*. BPA暴露对本体和子代胰岛β细胞转录组差异对比分析.环境化学, 2021, 40(02): 509-519.
