
路上云
博士,副教授,硕士研究生导师
E-mail: lushangyun.sxmu@aliyun.com
教育经历:
2016.9 – 2020.7中国农业大学,营养与食品安全专业,博士
2013.9 – 2016.7中国海洋大学,食品科学专业,硕士
2009.9 – 2013.7陕西师范大学,食品科学与工程专业,学士
工作经历
2024.12-至今山西医科大学公共卫生学院,营养与食品卫生学教研室,副教授
2020.10-2024.12山西医科大学公共卫生学院,营养与食品卫生学教研室,讲师
学术任职
山西省营养学会副秘书长
荣誉获奖
2022年公共卫生学院中青年教师教学基本功竞赛二等奖
教学情况
主要承担本科生《预防医学》、《营养与食品卫生学》课程,研究生《食物、营养与健康》课程;主持山西省高等学校教学改革创新项目1项(编号:J20230516)。
研究领域
营养与慢性疾病
代表性科研项目:
1.国家自然科学基金青年项目(编号:82304147),30万元,主持,在研。
2.山西医科大学博士启动基金(编号:XD2025),40万元,主持,在研。
3.山西省应用基础研究计划青年项目(编号:202103021223215),5万元,主持,已结题。
4.山西省教育厅高校科技创新计划项目(编号:2021-224),3万元,主持,已结题。
5.山西省博士启动基金(编号:SD2016),5万元,主持,已结题。
6.国家重点研发计划项目子课题(编号:2018YFC1603005-1),230万元,参与,已结题。
代表性论著:
1.Lu S, Xu Y, Zhang H, Liu Z, Xu J, Zheng B, Shi D, Qiu F. Glycyrol Relieves Ulcerative Colitis by Promoting the Fusion of ZO-1 with the Cell Membrane through the Enteric Glial Cells GDNF/RET Pathway. J Agric Food Chem. 2024 Jul 3;72(26):14653-14662. doi: 10.1021/acs.jafc.4c00239.
2.路上云,徐佳丽,许杨,等.甘草酚调节肠道菌群及其代谢产物激活自噬拮抗5-氟尿嘧啶致小鼠结肠损伤的机制研究[J].营养学报,2024,46(04):372-382.DOI:10.13325/j.cnki.acta.nutr.sin.20240801.001.
3.Lu S,Xu J,Xu Y, Liu Y, Shi D, Wang J, Qiu F. Glycyrol attenuates colon injury via promotion of SQSTM1/p62 ubiquitination and autophagy by inhibiting the ubiquitin-specific protease USP8, Journal of Functional Foods, 2023, 103.
4. Zhao S#,Lu S#,Fan L, Hu H*. Glycyrol Alone or in Combination with Gefitinib Is Effective against Gefitinib-Resistant HCC827GR Lung Cancer Cells, Applied Sciences-Basel, 2021, 11, 10526.
5.Lu S,Sun Z, Hu W, Yin S Yin S*, Zhao C, Hu H*. PD-L1 positively regulates MET phosphorylation through inhibiting PTP1B. Cancer Science, 2021, Doi: 10.1111/cas.14844.
6.Lu S,Liu S, Cui J, Liu X, Zhao C, Fan L, Yin S*, Hu H*. Combination of patulin and chlorpyrifos synergistically induces hepatotoxicity via inhibition of catalase activity and generation of reactive oxygen species. Journal of Agricultural and Food Chemistry. 2019, DOI:10.1021/acs.jafc.9b04814.
7.Lu S,Ye L, Yin S, Zhao C, Yan M, Liu X, Cui J, Hu H*. Glycyrol exerts potent therapeutic effect on lung cancer via directly inactivating T-LAK cell-originated protein kinase. Pharmacological Research. 2019,147:104366.
8.Lu S,Yin S, Zhao C, Fan L*, Hu H*. Synergistic anti-colon cancer effect of glycyrol and butyrate is associated with the enhanced activation of caspase-3 and structural features of glycyrol. Food and Chemical Toxicology. 2019, DOI: 10.1016/j.fct.2019.110952.
9.Lu S,Zuo T*. Effect of Food Additives on the Gut Microbiome in Relation to Human Health. Nutrition and Food Toxicology. 2018, 2(5):474-476.
10.Lu S,Zuo T, Zhang N, Shi H, Liu F, Wu J, Wang Y, Xue C, Tang Q*. High throughput sequencing analysis reveals amelioration of intestinal. dysbiosis by squid ink polysaccharide. Journal of Functional Foods, 2016, 20:506-515.
11.路上云,左涛,王江华,郑荣,王玉明,薛长湖,唐庆娟*. 16S rDNA克隆文库法分析两种鱿鱼墨多糖对小鼠肠道菌群多样性的影响[J].中国食品学报, 2016, 16(10):154-159.